European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations. [PDF]
United European Gastroenterol JPandanaboyana S +12 more
europepmc +1 more source
British Journal of Haematology, EarlyView.Summary To assess the cost‐effectiveness of blinatumomab plus chemotherapy for paediatric patients from Hong Kong public healthcare provider's perspective, a 10‐year Markov model was designed to simulate outcomes in paediatric patients with newly diagnosed standard‐risk B‐cell ALL at: (1) average risk and (2) high risk of relapse.
Mingjun Rui +7 more
wiley +1 more source
Extensive Emphysematous Necrotising Pancreatitis Presenting With Cullen's Sign Despite a Normal Serum Amylase Level. [PDF]
CureusAbdelgawwad W +4 more
europepmc +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Acute Hyponatremia as a Telling Complication of Necrotizing Pancreatitis and Perforated Cholecystitis After Percutaneous Cholecystostomy. [PDF]
ACG Case Rep JLee J, Kubey A.
europepmc +1 more source
Cancer Science, EarlyView.tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley +1 more source
Dynamics of in-hospital body composition changes in mild and moderately severe acute pancreatitis: trajectories and predictors. [PDF]
Front NutrSun D, Zhou X, Li H, Lin H.
europepmc +1 more source
Diagnostic Options in Graves' or Non‐Graves' Thyrotoxicosis: A Review for Clinical Practice
Clinical Endocrinology, EarlyView.ABSTRACT Objective Distinguishing Graves' disease (GD) from the other causes of thyrotoxicosis is essential for appropriate management. The clinical phenotype of GD has evolved over time and is currently more heterogenous and milder than in the past. Consequently, the differential diagnosis of thyrotoxicosis is often challenging.
Lorenzo Scappaticcio +7 more
wiley +1 more source
Pediatric Pancreatic Pseudocyst Presenting as a Solid Perigastric Mass: An Uncommon Diagnostic Pitfall. [PDF]
Case Rep PediatrMaisano G +7 more
europepmc +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
Cell Proliferation, EarlyView.m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source