Results 191 to 200 of about 166,885 (311)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Hypertriglyceridemia‑Induced Acute Pancreatitis Compared With Non-Hypertriglyceridemia Acute Pancreatitis: A Retrospective Case-Control Study. [PDF]

Health Sci Rep
Farhangiyan Z, Moradi L, Vaziri M, Lak E, Zaman F, Mohammadi S.   +5 more
europepmc   +1 more source

The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan, Karen Hon, Ruby E. Dawson, Teresa Weng, Jelena Solujic, Yu C. J. Chey, James D. Zuiani, Griffith B. Perkins, P. Toby Coates, Chris Drogemuller, Eddie Sanderlin, Lulu Huang, John Finnie, Stefan Rose‐John, Arash Badiei, Phan Nguyen, Brendan J. Jenkins, Mohamed I. Saad   +17 more
wiley   +1 more source

Air Everywhere: A Rare Post-ERCP Syndrome of Acute Pancreatitis, Pneumothorax, and Multicompartment Air Leak without Perforation. [PDF]

Clin Med Insights Case Rep
Hazzouri AA, Ziade M, Atallah K, Khoury ME, Bechara J, Attieh P, Mourad P.   +6 more
europepmc   +1 more source

Expanding Spectrum of FIG4‐Related Neurological Disorders of Lysosomal Homeostasis: Case Report and Overview of the Potential Genotype–Phenotype Correlations

Clinical Genetics, EarlyView.
FIG4 is essential for lysosomal homeostasis. FIG4‐related disorders present as a continuous spectrum from the juvenile lethality in Yunis‐Varon syndrome to an increased risk of amyotrophic lateral sclerosis (ALS) in adult life. FIG4‐related disorders comprise a novel group of disorders of lysosomal homeostasis and can be classified into severe ...
Pankaj Prasun, Matthew Rasberry
wiley   +1 more source

Gut or Vein? Enteral Nutrition Versus Total Parenteral Nutrition in Acute Pancreatitis: A Systematic Review. [PDF]

Cureus
Kaur H, Sharma A, Dimowo PK, Rajeev A, Shaikh SS, Mohammed L.   +5 more
europepmc   +1 more source

What Are Computer‐Assisted Methods Achieving in Fine‐Needle Aspiration Cytology of the Pancreas? A Systematic Review and Meta‐Analysis

Cytopathology, EarlyView.
This meta‐analysis demonstrates high diagnostic accuracy of computer‐assisted methods in pancreatic EUS‐FNA cytology (AUC 0.92–0.96) and supports an integrated, cytopathologist‐led workflow in which artificial intelligence functions as an adjunct to diagnostic interpretation and on‐site evaluation (ROSE). Created in BioRender. Mohamed Mirzan, A. (2026)
Al‐Amaan Mohamed Mirzan, Roberto Dina
wiley   +1 more source

Frequency and predictors of small intestinal bacterial overgrowth in acute pancreatitis. [PDF]

World J Gastrointest Pharmacol Ther
Kumbar C, Vaithiyam V, Reddy RT, Mehta K, Ahuja A, Kumar A, Dalal A, Sachdeva S.   +7 more
europepmc   +1 more source

Evaluation of the Safety, Efficacy and Pharmacokinetics of BGM0504 in Chinese Adults With Type 2 Diabetes: A Multicentre, Randomised, Controlled and Double‐Blind Phase II Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This study aimed to evaluate its safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in Chinese adults with T2DM and to preliminarily compare its efficacy and safety with semaglutide through multiple subcutaneous injections. Materials and Methods In this multicentre, randomised, placebo‐controlled and semaglutide‐positive‐
Ping Jin, Linong Ji, Yangqing Huang, Haifeng Ding, Daosheng Xie, Xiaohui Jiang, Xuemei Yuan, Zhao Cao, Haibin Zhang, Jiandong Yuan   +9 more
wiley   +1 more source

Pancreatic Calculi: Two Case Reports and Literature Review. [PDF]

Clin Med Insights Case Rep
Aby Hadeer R, Ghattas S, Tabche A, Salem J, Maalouf H, Al Hachem N, Wakim R.   +6 more
europepmc   +1 more source