Results 121 to 130 of about 45,095 (307)

Model‐Based Strategy for 6‐Mercaptopurine Treatment in Acute Lymphoblastic Leukemia Maintenance Phase: Prediction of 6‐TGN and 6‐MMP Concentrations to Optimize Treatment

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Introduction Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The pro‐drug 6‐mercaptopurine (6‐MP), essential during maintenance, is converted into active 6‐thioguanine (6‐TGN) and toxic 6‐methylmercaptopurine (6‐MMP) metabolites, resulting in marked variability in efficacy and toxicity.
Anne Ravix, Anaïs Maillat, Eva Choong, Chantal Csajka, Monia Guidi, Francesco Ceppi   +5 more
wiley   +1 more source

Magnetic Resonance Imaging as a Complementary Diagnostic Tool for Aplastic Anemia

American Journal of Hematology, Volume 101, Issue 5, Page 1074-1076, May 2026.
Jeanette Walter, Peter Isfort, Susanne Isfort, Jens Panse, Katharina Lindemann‐Docter, Tim H. Brümmendorf, Fabian Beier   +6 more
wiley   +1 more source

Olanzapine-induced Pancytopenia: Case Report

Medical Journal of Dr. D.Y. Patil Vidyapeeth
In the field of antipsychotic medicines, clozapine and olanzapine are both structurally and functionally similar. This case study describes a 35-year-old man with paranoid schizophrenia who experienced a rare case of olanzapine-induced pancytopenia.
A Prajnashree, S. K Someshwar, Arfa A Sayed, K P Abhirami, Sanatkumar B. Nyamagoud   +4 more
doaj   +1 more source

Hemophagocytic Macrophages in the Peripheral Blood of a Critically Ill Patient With COVID‐19 and RSV Infection

American Journal of Hematology, Volume 101, Issue 5, Page 1070-1071, May 2026.
Ashik Zala, Ahmed Sadek, Ahmed Elsaid, Ketan C. Patel, Maximiliano Ramia De Cap, Barbara J. Bain   +5 more
wiley   +1 more source

A Disproportionality Analysis of Immune Checkpoint Inhibitors in Combination With Platinum‐Based Agents Using the FDA Adverse Event Reporting System Database

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Objective Immune checkpoint inhibitors (ICIs) combined with platinum‐based compounds are commonly used in the treatment of certain malignant tumors. This study aims to analyze adverse events (AEs) associated with the combination therapy of ICIs and platinum‐based compounds by using the FAERS database.
Boyi Liu, Wenchao Zhang, Ruizhe Huang, Dinwen Liu, Jiaxing Liu, Ao Han, Yike Li, Danna Chen   +7 more
wiley   +1 more source

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Myeloma Presenting with Pancytopenia: Our Experience from a Tertiary Care Center in South India

Journal of Applied Hematology
BACKGROUND AND OBJECTIVES: Multiple myeloma commonly presents with anemia, but it is uncommon for patients to exhibit pancytopenia at initial presentation.
Shreya Patel, S. Josephine, Sri Gayathri
doaj   +1 more source

A Complex Inflammatory Triad: A Rare Case of Parry‐Romberg Syndrome With Systemic Lupus Erythematosus and Thyroiditis

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Parry‐Romberg Syndrome (PRS) is a rare disorder characterized by progressive unilateral facial atrophy, traditionally viewed as a localized scleroderma variant. Its rare coexistence with systemic lupus erythematosus (SLE) and autoimmune thyroiditis (AIT) suggests a broader inflammatory etiology, challenging the notion of PRS as a purely ...
Sakib Abrar, Fabiha Rahman Spriha, Sajjad Ghanim Al‐Badri, Md. Imran Hossain, Ibrahim Khalil   +4 more
wiley   +1 more source

Pennies for Your Thoughts: A Case Series of Pancytopenia Due to Zinc-Induced Copper Deficiency in the Same Patient [PDF]

, 2019
A 47-year-old schizophrenic male presented on three separate occasions with pancytopenia and sideroblastic anemia due to copper deficiency from massive zinc penny ingestion.
Aaron, Cynthia K., Bora, Keenan M., Dolcourt, Bram A., Paxton, James H.   +3 more
core  

Spongiotic Dermatitis: An Underrecognized Cutaneous Manifestation of Severe Uremia

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Spongiotic dermatitis may represent an underrecognized cutaneous manifestation of severe uremia. While uremic pruritus typically presents without primary skin eruptions, extreme uremic toxin accumulation can trigger inflammatory dermatologic changes. Recognition of atypical skin findings in chronic kidney disease patients may indicate systemic
Katrina Villegas, Ahmad Qatanani, Utku Ekin, Lance Alquran, Lan Wang, Sushilkumar Satish S. Gupta   +5 more
wiley   +1 more source