Results 111 to 120 of about 1,928,648 (313)

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Risk factors associated with the intensity of COVID-19 outbreaks in Canadian community settings: a retrospective analysis of outbreak-level surveillance data

BMC Public Health
Background The severity of COVID-19 outbreaks is disproportionate across settings (e.g., long-term care facilities (LTCF), schools) across Canada. Few studies have examined factors associated with outbreak severity to inform prevention and response.
Demy Dam, Michelle Chen, Erin E. Rees, Bethany Cheng, Lynn Sukkarieh, Erin McGill, Yasmina Tehami, Anna Bellos, Jonathan Edwin, Kaitlin Patterson   +9 more
doaj   +1 more source

Modern Pandemics: Recession and Recovery

, 2020
Chang Ma, John H. Rogers, Sili Zhou
openalex   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Mayaro Virus as the cause of Acute Febrile Illness in the Colombian Amazon Basin

Frontiers in Microbiology
IntroductionMayaro Fever (MF) is a tropical disease caused by the Mayaro virus (MAYV), with outbreaks documented in Latin America.MethodsA hospital-based fever surveillance in Leticia, Colombian Amazon, collected sera from 1,460 patients aged 5-89 ...
Laura S. Perez-Restrepo, Laura S. Perez-Restrepo, Karl Ciuoderis, Karl Ciuoderis, Jaime Usuga, Jaime Usuga, Isabel Moreno, Isabel Moreno, Vanessa Vargas, Vanessa Vargas, Angela J. Arévalo-Arbelaez, Angela J. Arévalo-Arbelaez, Michael G. Berg, Michael G. Berg, Gavin A. Cloherty, Gavin A. Cloherty, Juan Pablo Hernández-Ortiz, Juan Pablo Hernández-Ortiz, Juan Pablo Hernández-Ortiz, Jorge E. Osorio, Jorge E. Osorio, Jorge E. Osorio, Jorge E. Osorio   +22 more
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

A protocol for a living mapping review of global research funding for infectious diseases with a pandemic potential – Pandemic PACT [version 2; peer review: 2 approved, 1 approved with reservations]

Wellcome Open Research
The COVID CIRCLE initiative Research Project Tracker by UKCDR and GloPID-R and associated living mapping review (LMR) showed the importance of sharing and analysing data on research at the point of funding to improve coordination during a pandemic.
Zaharat Kadri-Alabi, Shanthi Levanita, Emilia Antonio, Georgina Humphreys, Adrian Bucher, Nusrat Jabin, Rodrigo Furst, Olena Seminog, Alice Norton, Omid Rohanian, Thomas Mendy   +10 more
doaj   +1 more source

Development of a measurement setup to detect the level of physical activity and social distancing of ageing people in a social garden during COVID-19 pandemic

, 2021
Sara Casaccia, Riccardo Naccarelli, Sara Moccia, Lucia Migliorelli, Emanuele Frontoni, Gian Marco Revel   +5 more
openalex   +2 more sources

Probability of informed trading during the COVID-19 pandemic: the case of the Romanian stock market [PDF]

, 2023
Cosmin-Octavian Cepoi, Victor Dragotă, Ruxandra Trifan, Andreea Iordache   +3 more
openalex   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source