Results 151 to 160 of about 1,195,920 (315)

Multifunctional Edged‐Satellite AuAg Nanoparticles‐Based Integration Platform for Screening, Validation, and Elimination of Vibrio Bacteria

Advanced Science, EarlyView.
A simple method is developed to synthesize multifunctional nanoparticles (NPs), AuAgNPs with edged satellites (ES‐AuAgNPs). These NPs demonstrate peroxidase‐like (POD‐like) activity, SERS ability, and antibacterial properties. Utilizing these multifunctional capabilities, a portable, syringe‐sized biosensor is created that integrates screening ...
Yixuan Wu, Jiadong Chen, Liyan Bi, Zhiyang Zhang, Xiaoyan Wang, Longwen Fu, Qian Yang, Jaebum Choo, Lingxin Chen   +8 more
wiley   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

Estimates of the Demand for Mechanical Ventilation in the United States During an Influenza Pandemic [PDF]

, 2015
Martin I. Meltzer, Anita Patel, Adebola Ajao, Scott Nystrom, Lisa M. Koonin   +4 more
openalex   +1 more source

Implications of COVID-19 pandemic for energy-use and energy saving household electrical appliances consumption behaviour in Malaysia

, 2021
Siti Indati Mustapa, Rajah Rasiah, Amar Hisham Jaaffar, Aisyah Abu Bakar, Zeittey Karmilla Kaman   +4 more
openalex   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Trends in Myopia Development Among Primary and Secondary School Students During the COVID-19 Pandemic: A Large-Scale Cross-Sectional Study [PDF]

, 2022
Jingfeng Mu, Haoxi Zhong, Meizhou Liu, Mingjie Jiang, Xinyi Shuai, Yanjie Chen, Long Wen, Shaochong Zhang   +7 more
openalex   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Burnout and Cardiovascular Risk in Healthcare Professionals During the COVID-19 Pandemic [PDF]

, 2022
Fayeza Alameri, Noura Aldaheri, Sarah Almesmari, Manea Basaloum, Nouf Albdulrahman Albeshr, Mecit Can Emre Simsekler, Nnamdi Valbosco Ugwuoke, Murat Dalkilinc, Mai Al Qubaisi, Luciana Aparecida Campos, Wael Almahmeed, Eman Alefishat, Hashel Al Tunaiji, Ovidiu Constantin Baltatu   +13 more
openalex   +1 more source

Unpublicized Pandemics [PDF]

Journal of Pastoral Care & Counseling: Advancing theory and professional practice through scholarly and reflective publications, 2021
openaire   +2 more sources

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source