Results 181 to 190 of about 1,928,648 (313)

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

The Role of Chest Imaging in Patient Management During the COVID-19 Pandemic

Chest, 2020
G. Rubin, C. Ryerson, L. Haramati, N. Sverzellati, J. Kanne, S. Raoof, N. Schluger, A. Volpi, J. Yim, Ian B. K. Martin, D. Anderson, C. Kong, T. Altes, A. Bush, S. Desai, J. Goldin, J. Goo, M. Humbert, Y. Inoue, H. Kauczor, F. Luo, P. Mazzone, M. Prokop, M. Rémy-Jardin, L. Richeldi, C. Schaefer-Prokop, N. Tomiyama, A. Wells, A. Leung   +28 more
semanticscholar   +1 more source

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

Metabolism, 2022
C. Boutari, C. Mantzoros
semanticscholar   +1 more source

The impact of the COVID-19 pandemic on the global burden of mental disorders: a counterfactual modeling study from 1990 to 2021. [PDF]

Transl Psychiatry
Chen M, Miao J, Chen C, Qu R, Zhou W, Qi J, Cao K, Wu X, Wang Y, Yang Y, Zhou J, Yan R, Dong N, Zhu C, Yang S.   +14 more
europepmc   +1 more source

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source

Increase in suicide following an initial decline during the COVID-19 pandemic in Japan

Nature Human Behaviour, 2021
Takanao Tanaka, S. Okamoto
semanticscholar   +1 more source

Regional patterns of excess mortality in Germany during the COVID-19 pandemic: a state-level analysis. [PDF]

R Soc Open Sci
Kuhbandner C, Reitzner M.
europepmc   +1 more source

Compartmentalization and Aggregation of Biomolecular Condensates in Crowded Hydrogels for Enhanced Nucleic Acid Diagnosis

Advanced Science, EarlyView.
A cell‐mimetic hydrogel compartment is proposed to enhance the efficiency of enzymatic reactions. The naturally porous structure of a crowded hydrogel can simulate the intracellular microenvironment, promoting the aggregation of biomolecules and activity of DNA polymerase through excluded volume effects and compartmentalization.
Fangbin Xiao, Tao Yang, Mei Fang, Xingyu Lin   +3 more
wiley   +1 more source

Shifting trends in influenza and rising HBoV cases: a comparative analysis over 3-winter seasons. [PDF]

BMC Infect Dis
Cetin M, Turan C, Yurumez C, Yurtseven A, Cicek C, Saz EU.   +5 more
europepmc   +1 more source

Assessment of online teaching in Hood College’s Department of Chemistry and Physics during the Covid-19 pandemic

, 2021
Samantha Kellers
openalex   +2 more sources