Results 211 to 220 of about 3,447,388 (399)

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

Expressions of pandemic fatigue on digital platforms: a thematic analysis of sentiment and narratives for infodemic insights

BMC Public Health
Background The infodemic accompanying the COVID-19 pandemic has led to an overwhelming amount of information, including questions, concerns and misinformation. Pandemic fatigue has been identified as a concern from early in the pandemic.
Becky K. White, Atsuyoshi Ishizumi, Lucy Lavery, Amy Wright, Tom Foley, Rhys O’Neill, Kimberly Rambaud, Ravi Shankar Sreenath, Cristiana Salvi, Ryoko Takahashi, Marcelo D’Agostino, Tim Nguyen, Sylvie Briand, Tina D. Purnat   +13 more
doaj   +1 more source

Peculiarities of teaching the oncology cycle in students of foreign faculty in conditions of the COVID-19 pandemic: the department’s experience

, 1970
A. V. Prokhach, В. Ф. Завізіон, Igor Bondarenko, M.I. KHODZHUZH   +3 more
openalex   +2 more sources

Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It By Gina Kolata. New York: Farrar, Straus and Giroux, 1999. 330 pp., illustrated, $25.00 [PDF]

, 2000
Doris J. Bucher
openalex   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

Peculiarities of using distance learning at Universities of Ukraine during the Pandemic period

, 1970
Natalia Shalova, Oksana Zarivna, N. KHIMAI   +2 more
openalex   +2 more sources

Influenza Pandemic Preparedness Planning Software [PDF]

, 2000
Gina Pugliese, Martin S. Favero
openalex   +1 more source

A Phase Separation‐Assisted Pre‐Enrichment Method for Ultrasensitive Respiratory Virus Detection

Advanced Science, EarlyView.
Conventional biomarker enrichment lacks versatility and specificity. Phase separation‐assisted pre‐enrichment (PSAP) is introduced for concurrent antigen (47×) and RNA (44×) enrichment. Tenfold and fivefold lower detection limits for SARS‐CoV‐2 and Influenza, respectively, were achieved.
Yang Cao, Pui Ngan Lau, Alex W.H. Chin, Zhuolin He, Christina C. K. Au Yeung, Kehao Zeng, Haisong Lin, Leo L. M. Poon, Ho Cheung Shum   +8 more
wiley   +1 more source

Satellite Broadcast on Preparing for the Next Influenza Pandemic [PDF]

, 2000

openalex   +1 more source

Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities

Advanced Science, EarlyView.
Self‐amplifying (saRNA), linear (linRNA), and circular (circRNA) mRNAs are compared under standardized conditions using lipid nanoparticles (LNPs) and pABOL polymer. saRNA achieved superior expression, while linRNA and circRNA performance varied based on untranslated region elements and delivery method.
Irafasha C. Casmil, Josh J. Friesen, Nuthan V. Bathula, Anneke Strumpel, Chia Hao Ho, Ilana Guez, Kristen Y. S. Kong, Andrew J. Varley, Shigeki J. Miyake‐Stoner, Parinaz Aliahmad, Nathaniel S. Wang, Andrew J. Geall, Anna K. Blakney   +12 more
wiley   +1 more source