Results 221 to 230 of about 3,447,388 (399)

Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles

open access: yesAdvanced Science, EarlyView.
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu   +13 more
wiley   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian   +7 more
wiley   +1 more source

Call to Duty: US Military Plastic Surgery Response to the Coronavirus Disease 2019 Pandemic

open access: yesPlastic and Reconstructive Surgery, Global Open, 2020
Scott Farber, MD   +2 more
doaj   +1 more source

Emergency COVID-19: A Surprising Pandemic [PDF]

open access: hybrid, 2001
Kamel Earar   +5 more
openalex   +1 more source

Rapid and Ultra‐Sensitive SARS‐CoV‐2 Subgenomic RNA Detection Using Single‐Molecule With a Large Transistor‐SiMoT Bioelectronic Platform

open access: yesAdvanced Electronic Materials, EarlyView.
The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia   +12 more
wiley   +1 more source

Smart Textile Systems for Loneliness Monitoring in Older People Care: A Review of Sensing and Design Innovations

open access: yesAdvanced Electronic Materials, EarlyView.
This review explores the potential of smart textile systems for monitoring loneliness in older adults. It presents key behavioral and physiological indicators of loneliness and evaluates recent sensing and design innovations in smart textile technology. The study identifies challenges and outlines opportunities for developing user‐centered, comfortable
Yi Zhou   +12 more
wiley   +1 more source

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