Results 31 to 40 of about 902,982 (267)

Influenza Pandemics [PDF]

, 2011
The recent H1N1 pandemic that emerged in 2009 has illustrated how swiftly a new influenza virus can circulate the globe. Here we explain the origins of the 2009 pandemic virus, and other twentieth century pandemics. We also consider the impact of the 2009 pandemic in the human population and the use of vaccines and antiviral drugs.
Elderfield, Ruth, Barclay, Wendy
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

West African Policy Dialogue—impulse for better data: progress towards better analytics and better decisions

BMC Proceedings
In a context of increasing efforts towards the establishment of a Regional Health Data Hub for the African Region, the 2024 West African Policy Dialogue brought together researchers and policymakers from seven West African countries in a two-day meeting ...
Gideon Kwarteng Acheampong, Fortress Yayra Aku, John Amuasi, Sylvia Annang, Silvia Argimon, Ernest Konadu Asiedu, Joseph Humphrey Kofi Bonney, Reinhard Busse, Benjamin Emikpe, Esteban Garcia-Gallo, Jonathan Mawutor Gmanyami, Anne Meierkord, Sam Kofi Newton, Bernard Nkrumah, Benjamin Nyakutsey, Daniel Opoku, Paul Elvis Onyango Ouma, Michael Owusu, Wilm Quentin   +18 more
doaj   +1 more source

Developing the next-generation of adenoviral vector vaccines

Human Vaccines & Immunotherapeutics
The COVID-19 pandemic saw the first extensive use of adenoviral vector vaccines, with over 3 billion doses produced during the first year of the pandemic alone and an estimated 6 million lives saved.
Alexander T. Sampson, Matěj Hlaváč, Adam C. T. Gillman, Bruno Douradinha, Sarah C. Gilbert   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Research prioritisation in preparedness for and response to outbreaks of high-consequence pathogens: a scoping review

BMC Medicine
Background Priority setting for research on epidemic/pandemic-prone pathogens is essential for the allocation of limited resources to optimise impact. It involves the identification of gaps in knowledge crucial to effective preparedness and response to ...
Emilia Antonio, Nicolas Pulik, Susan Khader Ibrahim, Adebisi Adenipekun, Shanthi Levanita, Isabel Foster, Dorothy Chepkirui, Eli Harriss, Louise Sigfrid, Alice Norton   +9 more
doaj   +1 more source

The Pandemic Within the Pandemic

, 2022
Background and aimThe third leading preventable cause of death in the United States is excessive alcohol consumption. Our study sought to assess the impact of the coronavirus disease 2019 (COVID-19) on hospitalizations for alcohol-related hepatitis at a community hospital system.
Sohal, Aalam, Khalid, Sameeha, Green, Victoria, Gulati, Alakh, Roytman, Marina   +4 more
openaire   +2 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Gaps in the global health research landscape for mpox: an analysis of research activities and existing evidence

BMC Medicine
Background Since December 2022, human cases of mpox in the Democratic Republic of the Congo (DRC) have risen at unprecedented rates. We identified a need for systematic mapping of the active research landscape and evidence, assessing their alignment with
Rodrigo Furst, Emilia Antonio, Marieke de Swart, Isabel Foster, Johannes Paolo Cerrado, Zaharat Kadri-Alabi, Susan Khader Ibrahim, Lauren Ashley, Duduzile Ndwandwe, Louise Sigfrid, Alice Norton   +10 more
doaj   +1 more source

At the Epicenter of COVID-19–the Tragic Failure of the Global Supply Chain for Medical Supplies

Frontiers in Public Health, 2020
The tragic failure of the global supply chain in the face of the current coronavirus outbreak has caused acute shortages of essential frontline medical devices and personal protective equipment, crushing fear among frontline health workers and causing ...
Sonu Bhaskar, Sonu Bhaskar, Sonu Bhaskar, Sonu Bhaskar, Jeremy Tan, Jeremy Tan, Marcel L. A. M. Bogers, Marcel L. A. M. Bogers, Marcel L. A. M. Bogers, Marcel L. A. M. Bogers, Timo Minssen, Timo Minssen, Timo Minssen, Hishamuddin Badaruddin, Hishamuddin Badaruddin, Simon Israeli-Korn, Simon Israeli-Korn, Simon Israeli-Korn, Henry Chesbrough, Henry Chesbrough, Henry Chesbrough   +20 more
doaj   +1 more source