Results 1 to 10 of about 3,585,461 (226)

CD4⁺ T-cell responses directed towards A/H5N1-derived haemagglutinin peptides increase in patients with seasonal influenza A virus infection. [PDF]

Clin Transl Immunology
Abstract Objectives Recent outbreak of influenza A/H5N1 viral infections in birds and mammals worldwide prompted renewed concerns over an emerging H5N1‐related influenza pandemic in the generally immunologically‐naive global population. Cross‐reactive CD4+ T cells between A/H1N1 and A/H5N1 subtypes targeting internal and surface influenza proteins have
Allen LF, Rowntree LC, Jenzen M, Hagen RR, Croft NP, James F, Martin GE, Purcell AW, Illing PT, Tong SYC, Cheng AC, Kotsimbos TC, Trubiano JA, Kedzierska K, Nguyen THO.   +14 more
europepmc   +2 more sources

Predicting the antigenic structure of the pandemic (H1N1) 2009 influenza virus hemagglutinin. [PDF]

PLoS ONE, 2010
The pandemic influenza virus (2009 H1N1) was recently introduced into the human population. The hemagglutinin (HA) gene of 2009 H1N1 is derived from "classical swine H1N1" virus, which likely shares a common ancestor with the human H1N1 virus that caused
Manabu Igarashi, Kimihito Ito, Reiko Yoshida, Daisuke Tomabechi, Hiroshi Kida, Ayato Takada   +5 more
doaj   +1 more source

Possible Increased Pathogenicity of Pandemic (H1N1) 2009 Influenza Virus upon Reassortment

Emerging Infectious Diseases, 2011
Since emergence of the pandemic (H1N1) 2009 virus in April 2009, three influenza A viruses—seasonal (H3N2), seasonal (H1N1), and pandemic (H1N1) 2009—have circulated in humans.
Eefje J.A. Schrauwen, Sander Herfst, Salin Chutinimitkul, Theo M. Bestebroer, Guus F. Rimmelzwaan, Albert D.M.E. Osterhaus, Thijs Kuiken, Ron A.M. Fouchier   +7 more
doaj   +1 more source

Pre-existing immunity with high neutralizing activity to 2009 pandemic H1N1 influenza virus in Shanghai population. [PDF]

PLoS ONE, 2013
Pre-existing immunity is an important factor countering the pandemic potential of an emerging influenza virus strain. Thus, studying of pre-existing immunity to the 2009 pandemic H1N1 virus (2009 H1N1) will advance our understanding of the pathogenesis ...
Xiaoqing Liu, Yuan Liu, Yanjun Zhang, Zhihui Chen, Ziwei Tang, Qingqiang Xu, Yue Wang, Ping Zhao, Zhongtian Qi   +8 more
doaj   +1 more source

No Association between 2008–09 Influenza Vaccine and Influenza A(H1N1)pdm09 Virus Infection, Manitoba, Canada, 2009

Emerging Infectious Diseases, 2012
We conducted a population-based study in Manitoba, Canada, to investigate whether use of inactivated trivalent influenza vaccine (TIV) during the 2008–09 influenza season was associated with subsequent infection with influenza A(H1N1)pdm09 virus during ...
Salaheddin M. Mahmud, Paul Van Caeseele, Gregory Hammond, Carol Kurbis, Tim Hilderman, Lawrence Elliott   +5 more
doaj   +1 more source

Clinical characteristics and outcomes among pediatric patients hospitalized with pandemic influenza A/H1N1 2009 infection [PDF]

Korean Journal of Pediatrics, 2011
PurposeThe purpose of this article is to describe the clinical and epidemiologic features and outcomes among children hospitalized with pandemic influenza A/H1N1 2009 infection.MethodsWe retrospectively reviewed the charts of hospitalized pediatric ...
Eun Lee, Ju-Hee Seo, Hyung-Young Kim, Shin Na, Sung-Han Kim, Ji-Won Kwon, Byoung-Ju Kim, Soo-Jong Hong   +7 more
doaj   +1 more source

Outbreak of pandemic influenza A/H1N1 2009 in Nepal

Virology Journal, 2011
Background The 2009 flu pandemic is a global outbreak of a new strain of H1N1 influenza virus. Pandemic influenza A (H1N1) 2009 has posed a serious public health challenge world-wide.
Shrestha Sirjana, Prakash KC Khagendra, Upadhyay Bishnu, Shakya Geeta, Adhikari Bal Ram, Dhungana Guna   +5 more
doaj   +1 more source

Monitoring and Characterization of Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Japan, 2009–2010

Emerging Infectious Diseases, 2011
To monitor and characterize oseltamivir-resistant (OR) pandemic (H1N1) 2009 virus with the H275Y mutation, we analyzed 4,307 clinical specimens from Japan by neuraminidase (NA) sequencing or inhibition assay; 61 OR pandemic (H1N1) 2009 viruses were ...
Makoto Ujike, Miho Ejima, Akane Anraku, Kozue Shimabukuro, Masatsugu Obuchi, Noriko Kishida, Xu Hong, Emi Takashita, Seiichiro Fujisaki, Kazuyo Yamashita, Hiroshi Horikawa, Yumiko Kato, Akio Oguchi, Nobuyuki Fujita, Masato Tashiro, Takato Odagiri   +15 more
doaj   +1 more source

Surveillance Lessons from First-wave Pandemic (H1N1) 2009, Northern California, USA

Emerging Infectious Diseases, 2010
After the appearance of pandemic (H1N1) 2009 in April 2009, influenza activity was monitored within the Kaiser Permanente Northern California division by using laboratory, pharmacy, telephone calls, and utilization (services patients received) data.
Roger Baxter
doaj   +1 more source

Use of Antiviral Drugs to Reduce Household Transmission of Pandemic (H1N1) 2009, United Kingdom

Emerging Infectious Diseases, 2011
The United Kingdom implemented a containment strategy for pandemic (H1N1) 2009 through administering antiviral agents (AVs) to patients and their close contacts.
Richard G. Pebody, Ross Harris, George Kafatos, Mary Chamberland, Colin Campbell, Jonathan S. Nguyen-Van-Tam, Estelle McLean, Nick Andrews, Peter J. White, Edward Wynne-Evans, Jon Green, Joanna Ellis, Tim Wreghitt, Sam Bracebridge, Chikwe Ihekweazu, Isabel Oliver, Gillian E. Smith, Colin Hawkins, Roland Salmon, Brian Smyth, Jim McMenamin, Maria Zambon, Nick F. Phin, John M. Watson   +23 more
doaj   +1 more source