Results 41 to 50 of about 1,575,835 (313)
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
Institutional Determinants of Stock Market Development in European Union Transition Economies
Stock markets have become an important market for long run fund flows between savers and investors and also a determinant of economic growth with the emergence of endogenous growth theories. This study investigates the impact of institutional development
Yilmaz Bayar
doaj
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
Corrupção Burocrática e Empreendedorismo: Uma Análise Empírica dos Estados Brasileiros [PDF]
Entrepreneurial activity performs an important role in a nation’s economic dynamics. Previous studies argue that institutional factors are correlated with the opening of new businesses, however, the literature is divergent as to the effect of ...
Felipe Luiz Neves Bezerra de Melo+2 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
: The strong increase in global demand for lithium, driven by the ion battery market and the use of this non-metallic mineral in various economic sectors such as mining (as a non-metallic and non-renewable mineral), health, technology, and geopolitical ...
Cristian Colther+2 more
doaj +1 more source
This study investigates and analyses empirically the impact of Foreign Direct Investment (FDI) inflows on the exports for a panel series of five large-scale manufacturing industries of Pakistan during the period 2000-2020.
Kamran Farid+3 more
doaj +1 more source
Predictive Regressions with Panel Data [PDF]
This paper analyzes panel data inference in predictive regressions with endogenous and nearly persistent regressors. The standard fixed effects estimator is shown to suffer from a second order bias; analytical results, as well as Monte Carlo evidence, show that the bias and resulting size distortions can be severe.
openaire +3 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Real time Data Acquisition of Solar Panel
We created a real-time acquisition system to track the voltage, current and temperature changes of the solar panel as we installed it in a charging regulator with a battery.
Youssef Rehouma+4 more
doaj