Results 41 to 50 of about 167,006 (298)

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du   +18 more
wiley   +1 more source

Depolymerization and Reuse of Polycarbonates: Emerging Classes, Mechanisms and Challenges

open access: yesAngewandte Chemie, EarlyView.
This review collects the latest developments in the area of chemical and catalytic polycarbonate recycling strategies and includes the controlled degradation of similar types of macromolecules. Apart from the main strategies for deconstruction, the key mechanistic features of these depolymerization processes are also discussed together with the ...
Davide Rigo   +4 more
wiley   +2 more sources

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

Affinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in Plants

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter   +10 more
wiley   +1 more source

Conformationally Driven Dual Fluorescence Properties of Higher Heteroacenes With Periodically Incorporated Boron Atoms

open access: yesAngewandte Chemie, EarlyView.
We herein report the synthesis of a new heteroheptacene derivative with periodically incorporated six boron atoms. This compound exhibits dual fluorescence attributed to two interconvertible conformers that result from a delicate balance between the extended π‐system and the steric demand of bulky aryl groups attached to the boron centers.
Takeshi Yokochi   +6 more
wiley   +2 more sources

Auxetic structures in layed furniture panels

open access: yes, 2018
Light honeycomb panels with auxetic cores have found numerous applications in the production of vehicles, boats and aircrafts. There are no such solutions in the furniture industry. It has been proposed to use several new structures of auxetic cores to construct sandwich furniture panels.
Smardzevsky, Jerzy, Prekrat, Silvana
openaire   +2 more sources

THE APPLICATION OF THE COMPUTER INTEGRATED MANUFACTURİNG TO FOREST PRODUCTS INDUSTRY

open access: yesForestist, 1994
The im pact of the appiication of C om puter In te g ra te d M an u factu rin g (CİM ) to Forest Products Ind u stry was investigated. The m ethods invostigated were: AUTOCAD system as a CAD system, CNC m achine for panel cutting, and for drilling ...
Hüseyin KOÇ
doaj   +1 more source

Annealing‐Induced Plasticity and Strengthening in Metallic Glasses

open access: yesAdvanced Science, EarlyView.
This work challenges the dogma that annealing inevitably embrittles metallic glasses. We demonstrate that sub‐Tg annealing, guided by positive mixing enthalpy and constrained kinetics, can drive a self‐organized compositional fluctuation that creates an interface‐free heterogeneous structure.
Yingjie Zhang   +17 more
wiley   +1 more source

A Knowledge Graph and Large Language Model Framework for Customized Manufacturing: A Case Study in Furniture Panel Production

open access: yesIEEE Access
Compared to traditional mass production, customized discrete manufacturing—such as furniture panel production—generates massive, heterogeneous, and highly dynamic data throughout its lifecycle (order processing, process design ...
Cunji Zhang   +3 more
doaj   +1 more source

The existence and persistence of household financial hardship [PDF]

open access: yes, 2012
We investigate the existence and persistence of financial hardship at the household level using data from the British Household Panel Survey. Our modelling strategy makes three important contributions to the existing literature on household finances ...
Brown, S., Ghosh, P., Taylor, K.
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