Results 101 to 110 of about 304,080 (307)
Ordnance Survey of Great Britain [cartographic material] : England & Wales.
, 1931 5th ed. Topographic map series of southern England and Wales with relief shown by contours and spot heights.; Panel title: Ordnance Survey one inch map.
Great Britain. Ordnance Survey.
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Political Science Research and MethodsPanel surveys and phone-based data collection are essential for survey research and are often used together due to the practical advantages of conducting repeated interviews over the phone. These tools are particularly critical for research in dynamic or
Ala Alrababah +5 more
doaj +1 more source
Health monitoring at the Robert Koch Institute – Effects of a change in study design on sample composition and prevalence estimates due to the start of the ‘Health in Germany’ Panel [PDF]
Journal of Health MonitoringBackground: The Robert Koch Institute (RKI) continuously monitors key health indicators in the general population by collecting data repeatedly. As changes in survey design can affect prevalence estimates and thus make interpreting trends difficult, the ...
Elvira Mauz +12 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Are Final Comments in Web Survey Panels Associated with Next-Wave Attrition?
Survey Research Methods, 2016 Near the end of a web survey respondents are often asked whether they have further comments. Such final comments are usually ignored, in part because open-ended questions are challenging to analyse.
Cynthia McLauchlan, Matthias Schonlau
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Ordnance survey of Great Britain, quarter inch, fifth series /
, 1957 Various eds. Map series of Great Britain showing roads, railroads, water features, antiquities, boundaries, light vessels, lighthouses, windmills, radio or TV stations, telephone call boxes, buildings, and woods.; Relief shown by contours, shading ...
Great Britain. Ordnance Survey.
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source