Results 81 to 90 of about 10,160,813 (305)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A COMPARATIVE ANALYSIS OF REAL AND PREDICTED INFLATION CONVERGENCE IN CEE COUNTRIES DURING THE ECONOMIC CRISIS [PDF]

open access: yesCES Working Papers, 2014
The main objective of this study is to make a comparative analysis of inflation convergence in Central-Eastern European countries (CEE countries) during the economic crisis over 2008-2013.
Mihaela Simionescu
doaj  

Small sample properties of CIPS panel unit root test under conditional and unconditional heteroscedasticity [PDF]

open access: yes
This paper used Monte Carlo simulations to analyze the small sample properties of cross-sectionally augmented panel unit root test (CIPS test). We considered situations involving two types of time-series heteroskedasticity (unconditional and ARCH) in the
HAMORI, Shigeyuki, HASHIGUCHI, Yoshihiro
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Dynamic relationship among agriculture-renewable energy-forestry and carbon dioxide (CO2) emissions: empirical evidence from GUAM countries

open access: yesEQA
Nowadays with the climate change the environmental degradation has became the crucial issue in the World. This study empirically investigates the impact of agriculture value-added, forest area, and renewable energy on CO2 emissions in GUAM union ...
Elcin Vaqif Nesirov   +2 more
doaj   +1 more source

Empirical study on the effect of carbon tax on GHG emissions in select nations [PDF]

open access: yesBusiness Analyst
PurposeThis study aims to understand the impact of carbon pricing on greenhouse gas emissions. It is necessary to evaluate the effectiveness of the carbon pricing mechanism on the ground level; therefore, this study provides valuable input about the ...
Ajay Kumar
doaj   +1 more source

A Panel-CADF Test for Unit Roots [PDF]

open access: yes, 2007
In this paper we propose the extension of the covariate-augmented Dickey Fuller (CADF) test for unit roots developed by Hansen (1995} to the panel case. We show that the extension is viable and gives power gains with respect to the time series approach. Particular attention is paid to cross-unit dependence.
Costantini, Mauro   +2 more
openaire   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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