Results 101 to 110 of about 1,911,183 (308)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
July report of the U.S. Congressional Oversight Panel describing their activities and findings regarding farm loan restructuring, including sections on agriculture markets, and farm credit ...
United States. Congressional Oversight Panel.
core
September Oversight Report [PDF]
September report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the results of the Treasury's Troubled Asset Relief Program(TARP) in mitigating the effects of the 2007 financial ...
United States. Congressional Oversight Panel.
core
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
April report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the state of the U.S.
United States. Congressional Oversight Panel.
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Islamic Banking Acceleration in Malaysia and Indonesia: Panel VAR Approach
Islamic banking acceleration has been the major theme discussed for years, indicating the importance of such topic to be reexamined comprehensively. This study is aimed to empirically examine several aspects and condition which may play a leading role in
Arif Widodo, Mohammad Adam Haekal
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
March report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the current state of mortgage performance across the country, including sections on foreclosures and current government ...
United States. Congressional Oversight Panel.
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

