Results 91 to 100 of about 29,116 (211)

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu   +4 more
wiley   +1 more source

Infectious agents and inflammation. The role of microbiota in autoimmune arthritis [PDF]

open access: yes, 2018
In higher vertebrates, mucosal sites at the border between the internal and external environments, directly interact with bacteria, viruses, and fungi.
D'Amelio, Raffaele   +2 more
core   +2 more sources

Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis [PDF]

open access: yes, 2018
Subclinical gut inflammation occurring in patients affected by spondyloarthritis (SpA) is correlated with the severity of spine inflammation. Several evidences indicate that dysbiosis occurs in SpA, and that may modulate intestinal permeability and ...
Ciccia F.   +3 more
core   +1 more source

Histopathological Findings of Appendix Specimens in Quiescent Ulcerative Colitis: Correlations With Clinical Outcomes in the ACCURE Trial

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background The ACCURE trial demonstrated that appendicectomy reduces relapse rates within 1 year in patients with ulcerative colitis (UC) in remission. We aimed to explore appendiceal histopathology in quiescent UC and assess its association with postoperative relapse. Methods Appendix specimens from Dutch participants in the ACCURE trial were
Eva Visser   +6 more
wiley   +1 more source

Gastroesophageal junction Paneth cell carcinoma with extensive cystic and secretory features – case report and literature review

open access: yesDiagnostic Pathology, 2019
Background Carcinomas composed predominantly or purely of malignant Paneth cells were rarely reported in gastrointestinal system. They have not been reported at gastroesophageal junction nor has the association with Barrett esophagus been explored.
Wenyi Luo   +2 more
doaj   +1 more source

Intestinal transplantation [PDF]

open access: yes, 1994
Intestinal transplantation is often the only alternative form of treatment for patients dependent on total parenteral nutrition for survival.
Andreas G. Tzakis, M.D   +9 more
core   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li   +5 more
wiley   +1 more source

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

open access: yesCommunications Biology
A recent single-cell survey of the small-intestinal epithelium suggests that mucosal pentraxin 2 (Mptx2) is a new Paneth cell marker, but its function and involved mechanism in the Paneth cell are still unknown. Therefore, we create Mptx2 knockout (Mptx2
Weihui Yan   +10 more
doaj   +1 more source

Requirement of Gαq/Gα11 Signaling in the Preservation of Mouse Intestinal Epithelial HomeostasisSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Proliferation, differentiation, and morphogenesis of the intestinal epithelium are tightly regulated by a number of molecular pathways. Coordinated action of intestine is achieved by gastrointestinal hormones, most of which exert these
Noboru Watanabe   +6 more
doaj   +1 more source

Micromanagement in the gut : microenvironmental factors govern colon mucosal biofilm structure and functionality [PDF]

open access: yes, 2015
The human gut microbiome provides us with functional features that we did not have to evolve ourselves and can be viewed as a structured microbial community that operates like a microbial organ within the human host.
De Weirdt, Rosemarie, Van de Wiele, Tom
core   +2 more sources

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