Results 161 to 170 of about 29,116 (211)
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The Lancet, 1967
Abstract 9 patients are described who were found to have a deficiency of Paneth cells in the small intestinal mucosa. 7 of these had the coeliac syndrome and 2 had a more normal jejunal biopsy. A clinical picture of severe malabsorption was almost constant and, in the patients with the coeliac syndrome, there was a failure to respond to a gluten-free ...
B, Creamer, I J, Pink
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Abstract 9 patients are described who were found to have a deficiency of Paneth cells in the small intestinal mucosa. 7 of these had the coeliac syndrome and 2 had a more normal jejunal biopsy. A clinical picture of severe malabsorption was almost constant and, in the patients with the coeliac syndrome, there was a failure to respond to a gluten-free ...
B, Creamer, I J, Pink
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Digestion, 1972
The secretion of Paneth cells in the rat has been stimulated by pilocarpine, the small intestinal secretions have been collected and their free amino acid concentrations measured. Comparison with a control group of animals not given pilocarpine showed a statistically significant increase in the free amino acid concentrations.
A E, Gent, B, Creamer
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The secretion of Paneth cells in the rat has been stimulated by pilocarpine, the small intestinal secretions have been collected and their free amino acid concentrations measured. Comparison with a control group of animals not given pilocarpine showed a statistically significant increase in the free amino acid concentrations.
A E, Gent, B, Creamer
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Paneth cells and their multiple functions
Cell Biology International, 2022AbstractThe small intestine mucosa is lined by specialized cells that form the crypt‐villus axis, which expands its surface. Among the six intestinal epithelial cell types, the Paneth cell is located at the base of the crypt, and it contains numerous granules in its cytoplasm, composed of antimicrobial peptides, such as defensins and lysozyme, and ...
Laylla Barreto e Barreto +3 more
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Cellular and Molecular Life Sciences (CMLS), 2002
Paneth cells (PCs) were described over a century ago as granulated cells located at the base of small intestinal crypts, the 'crypts of Lieberkühn.' Various histochemical staining procedures were developed that identified PCs based on their distinctive granule-staining pattern.
E M, Porter +3 more
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Paneth cells (PCs) were described over a century ago as granulated cells located at the base of small intestinal crypts, the 'crypts of Lieberkühn.' Various histochemical staining procedures were developed that identified PCs based on their distinctive granule-staining pattern.
E M, Porter +3 more
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The Lancet, 1967
Abstract Paneth cells are present in the intestinal crypts of many species, including man; an examination of the mucosal structure shows that Paneth cells accompany a morphological pattern of short crypts with concentrated mitotic and maturation activity. Absence of Paneth cells in man is accompanied by a shortening of the crypts, a lessening of crypt
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Abstract Paneth cells are present in the intestinal crypts of many species, including man; an examination of the mucosal structure shows that Paneth cells accompany a morphological pattern of short crypts with concentrated mitotic and maturation activity. Absence of Paneth cells in man is accompanied by a shortening of the crypts, a lessening of crypt
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Science of The Total Environment, 1985
Two histochemical methods, Timm's sulphide silver method and the selenium method reveal the presence of two pools of metal ions in the Paneth cells. Ultrastructurally one pool is located in the secretion granules, the other in the cytoplasm.
Danscher, G +3 more
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Two histochemical methods, Timm's sulphide silver method and the selenium method reveal the presence of two pools of metal ions in the Paneth cells. Ultrastructurally one pool is located in the secretion granules, the other in the cytoplasm.
Danscher, G +3 more
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Paneth Cells in Experimental Amyloidosis
Scandinavian Journal of Gastroenterology, 1977The effect of experimental amyloidosis on the morphology of the Paneth cells of the mouse was investigated by using light and fluorescence microscopy. Amyloidosis was induced by daily subcutaneous casein injections for 4 weeks. It was found that the number of secretory granules of the Paneth cells increased in the jejunum, but remained normal in the ...
A, Ahonen, O, Penttilä, E, Klinge
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Paneth cells and innate mucosal immunity
Current Opinion in Gastroenterology, 2010Recent evidence shows that disruption of Paneth cell homeostasis by induction of endoplasmic reticulum stress or autophagy, with consequent apoptosis, contributes to inflammation and morbidity in a variety of experimental mouse models.Recent advances show that proinflammatory mediators in Paneth cell dense core secretory granules mediate tumor necrosis
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