Results 11 to 20 of about 29,116 (211)
Secretory Sorcery: Paneth Cell Control of Intestinal Repair and HomeostasisSummary [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2021 Paneth cells are professional secretory cells that classically play a role in the innate immune system by secreting antimicrobial factors into the lumen to control enteric bacteria.
Paul Cray +2 more
doaj +2 more sources
Paneth Cell Secretion in vivo Requires Expression of Tmem16a and Tmem16f [PDF]
Gastro Hep Advances, 2022 Background and Aims: Paneth cells play a central role in intestinal innate immune response. These cells are localized at the base of small intestinal crypts of Lieberkuhn.
Rainer Schreiber +2 more
doaj +2 more sources
Pouchitis Is Associated with Paneth Cell Dysfunction and Ameliorated by Exogenous Lysosome in a Rat Model Undergoing Ileal Pouch Anal Anastomosis [PDF]
Microorganisms, 2023 Background: Pouchitis is a common complication of restorative proctocolectomy and ileal pouch anal anastomosis (IPAA) for ulcerative colitis (UC), significantly affecting the postoperative quality of life.
Yi Xu +5 more
doaj +2 more sources
Cdk5rap3 is essential for intestinal Paneth cell development and maintenance [PDF]
Cell Death and Disease, 2021 Intestinal Paneth cells are professional exocrine cells that play crucial roles in maintenance of homeostatic microbiome, modulation of mucosal immunity, and support for stem cell self-renewal.
Michaela Quintero +11 more
doaj +2 more sources
HNF4α Acts as Upstream Functional Regulator of Intestinal Wnt3 and Paneth Cell FateSummary [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: The intestinal epithelium intrinsically renews itself ex vivo via the proliferation of Lgr5+ intestinal stem cells, which is sustained by the establishment of an epithelial stem cell niche.
Christine Jones +3 more
doaj +2 more sources
Cells, 2021 Background: Previous studies in mice indicated that Paneth cells and c-Kit-positive goblet cells represent the stem cell niche of the small intestine and colon, respectively, partly by supporting Wnt and Notch activation.
Erika López-Arribillaga +8 more
doaj +1 more source
Starvation Compromises Paneth Cells [PDF]
The American Journal of Pathology, 2011 Lack of enteral feeding, with or without parenteral nutritional support, is associated with increased intestinal permeability and translocation of bacteria. Such translocation is thought to be important in the high morbidity and mortality rates of patients who receive nothing by mouth. Recently, Paneth cells, important constituents of innate intestinal
Hodin, C.M.I. +8 more
openaire +3 more sources
The Paneth Cell: The Curator and Defender of the Immature Small Intestine
Frontiers in Immunology, 2020 Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their cytoplasm.
Shiloh R. Lueschow +2 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2023 Deoxynivalenol (DON) is a common toxin in grains and feeds, and DON exposure triggers severe small intestinal injury and inflammation, which harms the health of humans and livestock.
Chenbin Cui +6 more
doaj +1 more source
Ileal Mucosal and Fecal Pancreatitis Associated Protein Levels Reflect Severity of Salmonella Inflection in Rats [PDF]
, 2017 Background Microbial infections induce ileal pancreatitis-associated protein/regenerating gene III (PAP/RegIII) mRNA expression. Despite increasing interest, little is known about the PAP/RegIII protein.
Ampting, M.T.J., van +7 more
core +5 more sources