Results 101 to 110 of about 28,981 (212)

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

open access: yesDisease Models & Mechanisms, 2019
Paneth cells are key epithelial cells that provide an antimicrobial barrier and maintain integrity of the small-intestinal stem cell niche. Paneth cell abnormalities are unfortunately detrimental to gut health and are often associated with digestive ...
Emily J. Jones   +19 more
doaj   +1 more source

Intestinal transplantation [PDF]

open access: yes, 1994
Intestinal transplantation is often the only alternative form of treatment for patients dependent on total parenteral nutrition for survival.
Andreas G. Tzakis, M.D   +9 more
core   +1 more source

Paneth cells [PDF]

open access: yesCurrent Biology, 2014
van Es, Johan H, Clevers, Hans
openaire   +2 more sources

Modelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal crypt.

open access: yesPLoS ONE, 2012
We developed a slow structural relaxation model to describe cellular dynamics in the crypt of the mouse small intestine. Cells are arranged in a three dimensional spiral the size of which dynamically changes according to cell production demands of ...
Carmen Pin   +2 more
doaj   +1 more source

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis [PDF]

open access: yes, 2016
Objective. To investigate the expression and tis- sue distribution of Th9-related cytokines in patients with psoriatic arthritis (PsA). Methods. Quantitative gene expression analysis of Th1, Th17, and Th9 cytokines was performed in intestinal biopsy ...
ALESSANDRO, Riccardo   +17 more
core   +1 more source

Requirement of Gαq/Gα11 Signaling in the Preservation of Mouse Intestinal Epithelial HomeostasisSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Proliferation, differentiation, and morphogenesis of the intestinal epithelium are tightly regulated by a number of molecular pathways. Coordinated action of intestine is achieved by gastrointestinal hormones, most of which exert these
Noboru Watanabe   +6 more
doaj   +1 more source

GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress [PDF]

open access: yes, 2017
Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium.
Kraft, Crystal   +5 more
core   +2 more sources

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]

open access: yes, 2009
Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
core   +1 more source

Paneth Cell-Like Component in Prostate Cancer - Case Report

open access: yesActa Clinica Croatica, 2018
Prostate adenocarcinoma with Paneth cell-like neuroendocrine differentiation is a rare entity. Foci of scattered cells and small clusters are found in the majority of described cases, although cases with predominant Paneth cell-like features have also ...
Bernardica Jurić   +3 more
doaj   +1 more source

Best of United European Gastroenterology Week 2025

open access: yes
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
Iuliana Nenu   +3 more
wiley   +1 more source

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