The deubiquitinase OTUD4 inhibits the expression of antimicrobial peptides in Paneth cells to support intestinal inflammation and bacterial infection. [PDF]
Yu K +6 more
europepmc +1 more source
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]
Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan +13 more
core
Human intelectin-2 (ITLN2) is selectively expressed by secretory Paneth cells. [PDF]
Nonnecke EB +6 more
europepmc +1 more source
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease. [PDF]
Shi J +12 more
europepmc +1 more source
Efferocytosis by Paneth cells within the intestine. [PDF]
Shankman LS +7 more
europepmc +1 more source
Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn’s disease [PDF]
Ahmadian +21 more
core +2 more sources
Intestinal commensal microbiota and cytokines regulate Fut2+ Paneth cells for gut defense. [PDF]
Kamioka M +17 more
europepmc +1 more source
The Paneth cell, a secretory cell of the small intestine, expresses numerous host defense proteins, and is hypothesized to play an important role in host defense against infection.
Gill Diamond +19 more
doaj +1 more source
Paneth Cells Protect against Acute Pancreatitis via Modulating Gut Microbiota Dysbiosis. [PDF]
Fu Y +9 more
europepmc +1 more source

