Results 171 to 180 of about 28,981 (212)
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Cellular and Molecular Life Sciences (CMLS), 2002
Paneth cells (PCs) were described over a century ago as granulated cells located at the base of small intestinal crypts, the 'crypts of Lieberkühn.' Various histochemical staining procedures were developed that identified PCs based on their distinctive granule-staining pattern.
E M, Porter +3 more
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Paneth cells (PCs) were described over a century ago as granulated cells located at the base of small intestinal crypts, the 'crypts of Lieberkühn.' Various histochemical staining procedures were developed that identified PCs based on their distinctive granule-staining pattern.
E M, Porter +3 more
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The Lancet, 1967
Abstract Paneth cells are present in the intestinal crypts of many species, including man; an examination of the mucosal structure shows that Paneth cells accompany a morphological pattern of short crypts with concentrated mitotic and maturation activity. Absence of Paneth cells in man is accompanied by a shortening of the crypts, a lessening of crypt
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Abstract Paneth cells are present in the intestinal crypts of many species, including man; an examination of the mucosal structure shows that Paneth cells accompany a morphological pattern of short crypts with concentrated mitotic and maturation activity. Absence of Paneth cells in man is accompanied by a shortening of the crypts, a lessening of crypt
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Science of The Total Environment, 1985
Two histochemical methods, Timm's sulphide silver method and the selenium method reveal the presence of two pools of metal ions in the Paneth cells. Ultrastructurally one pool is located in the secretion granules, the other in the cytoplasm.
Danscher, G +3 more
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Two histochemical methods, Timm's sulphide silver method and the selenium method reveal the presence of two pools of metal ions in the Paneth cells. Ultrastructurally one pool is located in the secretion granules, the other in the cytoplasm.
Danscher, G +3 more
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Paneth Cells in Experimental Amyloidosis
Scandinavian Journal of Gastroenterology, 1977The effect of experimental amyloidosis on the morphology of the Paneth cells of the mouse was investigated by using light and fluorescence microscopy. Amyloidosis was induced by daily subcutaneous casein injections for 4 weeks. It was found that the number of secretory granules of the Paneth cells increased in the jejunum, but remained normal in the ...
A, Ahonen, O, Penttilä, E, Klinge
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Paneth cells and innate mucosal immunity
Current Opinion in Gastroenterology, 2010Recent evidence shows that disruption of Paneth cell homeostasis by induction of endoplasmic reticulum stress or autophagy, with consequent apoptosis, contributes to inflammation and morbidity in a variety of experimental mouse models.Recent advances show that proinflammatory mediators in Paneth cell dense core secretory granules mediate tumor necrosis
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Paneth Cell Adenoma of the Stomach
The American Journal of Surgical Pathology, 1989A case of Paneth cell adenoma of the stomach in a 75-year-old woman is reported. At histological examination, a tubular adenoma with low-grade (moderate) dysplasia was found. The dysplastic cells had distinct coarse cytoplasmic granules that stained red with eosin and PAS but were negative with alcian blue pH 2.5.
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Trypsin-Like Immunoreactivity in Human Paneth Cells
Digestion, 1984Human intestinal Paneth cells characterized by their content of lysozyme were shown to contain cationic trypsin immunoreactivity. This trypsin-like immunoreactivity was shown in the Paneth cells at their normal localization at the basis of the crypts of Lieberkühn and also in Paneth cells of metaplastic areas in gastric mucosa. This original finding is
M, Bohe +3 more
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Paneth cells—guardians of the gut cell hatchery
Nature Immunology, 2000Protection of the small intestine from harmful bacteria is a never-ending job. Paneth cells of the intestinal crypts function as prime producers of defensins in response to the microbial onslaught of the gut.
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The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death
Nature, 2022Jordan E Axelrad +2 more
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