Results 51 to 60 of about 3,148,952 (332)

Anxious‐depressive attack and rejection sensitivity—Toward a new approach to treatment‐resistant depression

open access: yesNeuropsychopharmacology Reports
This paper aimed to find clues to treatment‐resistant depression (TRD) solutions. Depression comorbid with anxiety is often treatment‐resistant where anxious‐depressive attack (ADA) often lurks.
Hisanobu Kaiya
doaj   +1 more source

Panic disorders: The role of genetics and epigenetics

open access: yesAIMS Genetics, 2018
Panic disorder is characterized by symptoms with abrupt surges of fear with palpitations, sweating, trembling, heat sensations. Considering its disease burden on each individual and on society, understanding its etiology is important.
Eun Jeong Kim, Yong-Ku Kim
doaj   +1 more source

Fear of memories: the nature of panic in posttraumatic stress disorder [PDF]

open access: yesEuropean Journal of Psychotraumatology, 2012
Background: Although there is increasing evidence that panic attacks are common in posttraumatic stress disorder (PTSD), little is known if posttraumatic panic is comparable to panic attacks observed in panic disorder (PD). Objective: This study examined
Amy Joscelyne   +3 more
doaj   +1 more source

Enhancing panic disorder treatment with mobile-aided case management: an exploratory study based on a 3-year cohort analysis

open access: yesFrontiers in Psychiatry, 2023
BackgroundIndividuals with panic disorder frequently face ongoing symptoms, suboptimal treatment adherence, and increased relapse rates. Although mobile health interventions have shown promise in improving treatment outcomes for numerous mental health ...
Chan-hen Tsai   +4 more
doaj   +1 more source

Disgust implicated in obsessive-compulsive disorder [PDF]

open access: yes, 1997
Psychiatric classificatory systems consider obsessions and compulsions as forms of anxiety disorder. However, the neurology of diseases associated with obsessive-compulsive symptoms suggests the involvement of fronto-striatal regions likely to be ...
A. J. Calder   +11 more
core   +2 more sources

Deciphering Neural Mechanisms Underlying Marmoset Dynamic Natural Behaviors Using a Miniaturized Wireless Large‐Scale Coverage Neural Recorder

open access: yesAdvanced Science, EarlyView.
This study introduces a miniaturized wireless neural recording system integrated with custom‐designed 120‐channel µECoG arrays, engineered for monitoring brain activities in freely behaving marmosets. The system can capture and characterize behavior‐specific neural signals, including drinking‐related activation, pre‐vocalization anticipatory responses,
Hongru Liu   +22 more
wiley   +1 more source

Distinct panicogenic activity of sodium lactate and cholecystokinin tetrapeptide in patients with panic disorder

open access: yesEuropean Journal of Psychotraumatology, 2012
Rationale : The validity of experimentally induced panic attacks as a model to study the pathophysiology of panic disorder has been questioned. Unspecific, unpleasant and aversive effects as well as specific patterns of psycho vegetative symptoms ...
Katharina Gaudlitz   +2 more
doaj   +1 more source

Efficacy of the Unified Protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disorders [PDF]

open access: yes, 2018
OBJECTIVE: This study aimed to examine whether the Unified Protocol (UP), a transdiagnostic cognitive-behavioral therapy for emotional disorders (i.e., anxiety, mood, and related disorders), is efficacious in the treatment of co-occurring emotional ...
Ametaj, Amanda   +6 more
core   +2 more sources

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li   +14 more
wiley   +1 more source

Childhood Internalizing and Externalizing Problems Predict the Onset of Clinical Panic Attacks over Adolescence: The TRAILS Study [PDF]

open access: yes, 2012
Background: Panic attacks are a source of individual suffering and are an independent risk factor for later psychopathology. However, much less is known about risk factors for the development of panic attacks, particularly during adolescence when the ...
Mathyssek, C.M. (Christina)   +3 more
core   +1 more source

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