Results 51 to 60 of about 1,337,518 (284)

Psychological and Neurodevelopmental Correlates of Extreme Demand Avoidance in a Clinical Sample, an Exploratory Study

Autism Research, EarlyView.
ABSTRACT Extreme/pathological demand avoidance (EDA) is a behavioral profile characterized by the avoidance of everyday demands, with significant impact on the individuals and those around them. Little is understood regarding the correlates and drivers of EDA; understanding these better may lead to targeted interventions and support strategies.
Oliver Lack, Matthew J. Hollocks, Gillian Baird, Ann Ozsivadjian, Michael Absoud, Francesca Happé, Emily Simonoff   +6 more
wiley   +1 more source

Panic disorder and hyperventilation [PDF]

Arquivos de Neuro-Psiquiatria, 1999
Respiratory abnormalities are associated with anxiety, particularly with panic attacks. Symptoms such as shortness of breath, "empty-head" feeling, dizziness, paresthesias and tachypnea have been described in the psychiatric and respiratory physiology related to panic disorder.
NARD, ANTONIO EGIDIO, VALENÇA, ALEXANDRE M., NASCIMENTO, ISABELLA, MEZZASALMA, MARCO A., ZIN, WALTER   +4 more
openaire   +4 more sources

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Environmental impact of antidepressants: Is a new prescription framework possible?

British Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi, Valentina Giunchi, Michael Thiede, Elisa Sangiorgi, Marco Menchetti, Elisabetta Poluzzi   +5 more
wiley   +1 more source

Panic disorder during pregnancy: A scoping review

Heliyon
Background: Panic Disorder is a serious anxiety disorder, and one of the severe mental problems that impacts mothers’ mental health and fetal health as well.
Eman Al-Awabdeh, Lubna Abu Shaikha, Abdelrahman Salameh, Jafar Alasad Alshraideh   +3 more
doaj   +1 more source

The Neurobiology of Panic: A Chronic Stress Disorder

Chronic Stress, 2017
Panic disorder is an often chronic and impairing human anxiety syndrome, which frequently results in serious psychiatric and medical comorbidities. Although, to date, there have been many advances in the diagnosis and treatment of panic disorder, its ...
Andrew W. Goddard
doaj   +1 more source

Clinical profile and changes in values of mean platelet volume among panic disorder patients

Archives of Mental Health, 2018
Context: The serotonin system is involved in the pathophysiology of anxiety disorders, but it is not practical to measure the serotonin levels inside the brain. Peripheral serotonin activity may reflect the central serotonergic function.
Sanjay Yalamanchili, Sai Kiran Pasupula, Raviteja Chilukuri   +2 more
doaj   +1 more source

Experimental Drugs for Panic Disorder: An Updated Systematic Review

, 2021
Daniela Caldirola,1,2 Alessandra Alciati,1– 3 Francesco Cuniberti,1,2 Giampaolo Perna1,2 1Department of Biomedical Sciences, Humanitas University, Milan, 20090, Italy; 2Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital ...
Cuniberti, Francesco, Caldirola D, Perna, Giampaolo, Perna G, Alciati A, Alciati, Alessandra, Cuniberti F, Caldirola, Daniela   +7 more
core   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor, Stefano Comai, Gianfranco Pasut, Franco Folli, Marco Gentilucci, Negar Gharavi, Sofia Raitsin, Thuy Van Nguyen, Marco Pappagallo, Andrea Mattarei, Paolo L. Manfredi, Sara De Martin   +11 more
wiley   +1 more source

Unsupervised machine learning for multi‐system adverse event pattern detection in pharmacovigilance: A proof‐of‐concept analysis of fluoroquinolone reports in FAERS

British Journal of Clinical Pharmacology, EarlyView.
. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo, Sheikh S. Abdullah, Kamran Sedig, Flory T. Muanda   +3 more
wiley   +1 more source