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Staphylococcal Leukocidin, Panton-Valentine Type
Journal of Toxicology: Toxin Reviews, 1985AbstractThe Panton-Valentine leukocidin produced by most strains of S. aureus attacks polymorphonuclear leukocytes and macrophages but not other cell types. The toxin, discovered by van de Velde in 1894, was distinguished clearly from leukocyte-damaging hemolysins by the studies of Panton and Valentine. Purified for the first time by Woodin in 1960, it
Piotr L. Grójec, Janusz Jeljaszewicz
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Gene sequences and specific detection for Panton-Valentine leukocidin
Biochemical and Biophysical Research Communications, 2005A new category of methicillin-resistant Staphylococcus aureus (MRSA), called community-acquired MRSA (CA-MRSA), has emerged worldwide. In contrast to previous MRSA, most CA-MRSA carries the Panton-Valentine leukocidin (PVL) genes (lukPVSF) as a virulence genetic trait.
Saori, Nakagawa +8 more
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Diagnosis and treatment of Panton–Valentine leukocidin (PVL)-associated staphylococcal pneumonia
International Journal of Antimicrobial Agents, 2007Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus is emerging as a serious problem worldwide. Whilst usually causing skin and soft-tissue infections, particularly recurrent abscesses, there has in the last 10 years been an increase in the incidence of an associated devastating pneumonia affecting previously healthy young people and ...
exaly +3 more sources
A case of epididymitis associated with Panton–Valentine leukocidinStaphylococcus aureus
Sexually Transmitted Infections, 2012A new pattern of disease caused by Panton–Valentine leukocidin (PVL)-positive strains ofStaphylococcus aureusis emerging in the UK and worldwide. Community-associated methicillin-resistantS aureus(MRSA) is more likely to produce PVL, a pore-forming cytotoxin inducing leucocyte lysis, which often infects young healthy individuals.
Malini, Raychaudhuri, Pei Ru, Chew
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Brain Abscess due to Panton–Valentine Leukocidin-Positive Staphylococcus aureus
Infection, 2008Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that exhibits highly specific lytic activity against polymorphonuclear cells, monocytes, and macrophages. A 34-year-old man admitted for right parietal brain abscess and thickened dura mater in close proximity to a lytic bone lesion is presented.
A, Ramos +4 more
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Pediatric Infectious Disease Journal, 2012
Infections caused by Panton-Valentine leukocidin (PVL)-producing strains of Staphylococcus aureus have been reported with increasing frequency. However, the role of PVL in the pathogenesis of invasive staphylococcal infection is controversial. It is interesting to note that the role played by PVL may depend on the site of infection; although an ...
Nicole, Ritz, Nigel, Curtis
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Infections caused by Panton-Valentine leukocidin (PVL)-producing strains of Staphylococcus aureus have been reported with increasing frequency. However, the role of PVL in the pathogenesis of invasive staphylococcal infection is controversial. It is interesting to note that the role played by PVL may depend on the site of infection; although an ...
Nicole, Ritz, Nigel, Curtis
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Staphylococcus aureus Panton-Valentine Leukocidin Causes Necrotizing Pneumonia
Science, 2007The Staphylococcus aureus Panton-Valentine leukocidin (PVL) is a pore-forming toxin secreted by strains epidemiologically associated with the current outbreak of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and with the ...
Maria, Labandeira-Rey +11 more
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Necrotising pneumonia, Staphylococcus aureus and Panton-Valentine leukocidin
Intensive Care Society. Journal, 2008The Panton-Valentin leukocidin (PVL) strain of meticillin-resistant Staphylococcus aureus (MRSA) is producing a new pattern of MRSA-related disease in the UK and world-wide. PVL is one of several extracellular cytotoxins produced by Staphylococcus aureus, and is usually associated with skin and soft tissue infections. PVL MRSA is uncommon in hospitals,
McGrath, Brendan, Broadfield, Emma
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Panton-valentine leukocidin-positive MRSA, Shanghai, China
2012link_to_subscribed_fulltext
Han, LZ +7 more
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The Staphylococcal Panton-Valentine Leukocidin (PVL)
2018Paweł Nawrotek +2 more
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