Results 41 to 50 of about 76,300 (242)

Paper-Based Screen-Printed Ionic-Liquid/Graphene Electrode Integrated with Prussian Blue/MXene Nanocomposites Enabled Electrochemical Detection for Glucose Sensing

Biosensors, 2022
As glucose biosensors play an important role in glycemic control, which can prevent the diabetic complications, the development of a glucose sensing platform is still in needed.
Wisanu Niamsi, Nutcha Larpant, Pramod K. Kalambate, Vitsarut Primpray, Chanpen Karuwan, Nadnudda Rodthongkum, Wanida Laiwattanapaisal   +6 more
doaj   +1 more source

Paper-Based Analytical Devices Coupled with Fluorescence Detection and Smartphone Imaging: Advances and Applications

Sensors
Paper-based analytical devices have emerged as a versatile and cost-effective platform for on-site chemical and biological analysis. The integration of fluorescence detection with smartphone imaging has significantly enhanced the analytical performance ...
Constantinos K. Zacharis
doaj   +1 more source

3D Printed Paper-Based Microfluidic Analytical Devices [PDF]

Micromachines, 2016
As a pump-free and lightweight analytical tool, paper-based microfluidic analytical devices (μPADs) attract more and more interest. If the flow speed of μPAD can be programmed, the analytical sequences could be designed and they will be more popular.
Yong He 0005, Qing Gao, Wen-Bin Wu, Jing Nie, Jianzhong Fu   +4 more
openaire   +3 more sources

Simple Microfluidic Paper-Based Analytical Device (μ-PAD) Coupled with Smartphone for Mn(II) Detection Using Tannin as a Green Reagent

Indonesian Journal of Chemistry, 2023
The development of a simple yet greener microfluidic paper-based analytical device (μ-PAD) for on-site detection of Mn(II) in various types of waters using tannin as a natural reagent was described.
Fidelis Nitti, Wendelina Archangela Ati, Philiphi de Rozari, Pius Dore Ola, David Tambaru, Luther Kadang   +5 more
doaj   +1 more source

The design of paper-based electroanalytical microfluidic device coupled with post-synthesized molecularly imprinted polymers (rGO/Au@Ag2S/PANI/polyacrylamide) for the detection of streptomycin

Sensors and Actuators Reports
A highly sensitive three-electrode paper-based microfluidic device has been developed for determinate of streptomycin. Ag/GQD/chitosan nano ink was used to construct reference and counter electrodes and Au@Ag2S/GQD/chitosan nano ink was used to construct
Mina Adampourezare, Karim Asadpour-Zeynali, Miguel de la Guardia, Jafar Ezzati Nazhad Dolatabadi   +3 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Electrophoretic separations on Parafilm-paper-based analytical devices

Sensors and Actuators B: Chemical, 2018
Microfluidic paper-based analytical devices (mPADs) have gained significant attention in recent years for applications ranging from clinical diagnostics to environmental testing. However, separation on mPADs remain challenging to implement, particularly in complex samples.
Jaruwan Mettakoonpitak, Charles S. Henry
openaire   +3 more sources