Results 91 to 100 of about 40,935,335 (372)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Alkylated Phosphorylated Fibers: A New Substitute for Silicone in Release Paper Manufacturing
BioResources, 2023 The production of release coatings has been increasing in recent years because of their use in various fields. However, commercially available release coatings are regarded as non-recyclable. As a consequence, the repulping of these residues is difficult,
Lahbib Abenghal +2 more
doaj
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley +1 more source
BioResources, 2023 Paper, which is in fact a very complex cellulose-based product derived from different lignocellulosic resources, is usually regarded as a simple omnipresent commodity in our lives.
Carmen-Alice Teaca
doaj
Piezoelectric Polymer and Paper Substrates: A Review
Sensors, 2018 Polymers and papers, which exhibit piezoelectricity, find a wide range of applications in the industry. Ever since the discovery of PVDF, piezo polymers and papers have been widely used for sensor and actuator design.
Kiran Kumar Sappati, Sharmistha Bhadra
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Data‐driven performance metrics for neural network learning
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri +2 more
wiley +1 more source
Non-Destructive Evaluation of Historical Paper Based on pH Estimation from VOC Emissions
Sensors, 2007 Volatile organic compounds (VOCs) emitted from materials during degradationcan be a valuable source of information. In this work, the emissions of furfural and aceticacid from cellulose were studied using solid-phase micro-extraction (SPME) incombination
Boris Pihlar +4 more
doaj +1 more source