Results 111 to 120 of about 512,921 (340)

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

A Spectroscopy Solution for Contactless Conductivity Detection in Capillary Electrophoresis

Micromachines
This paper introduces a novel contactless single-chip detector that utilizes impedance-to-digital conversion technology to measure impedance in the microfluidic channel or capillary format analytical device.
Tomas Drevinskas, Audrius Maruška, Hirotaka Ihara, Makoto Takafuji, Linas Jonušauskas, Domantas Armonavičius, Mantas Stankevičius, Kristina Bimbiraitė-Survilienė, Elzbieta Skrzydlewska, Ona Ragažinskienė, Yutaka Kuwahara, Shoji Nagaoka, Vilma Kaškonienė, Loreta Kubilienė   +13 more
doaj   +1 more source

Lateral Separation of Macromolecules and Polyelectrolytes in Microlithographic Arrays

, 1997
A new approach to separation of a variety of microscopic and mesoscopic objects in dilute solution is presented. The approach takes advantage of unique properties of a specially designed separation device (sieve), which can be readily built using already
A. Ajdari, B. H. Zimm, D. Long, D. M. Hawcroft, Deniz Ertaş, G. W. Slater, J. L. Barrat, K. Hannig, L. S. Lerman, M. Doi, M. Magnasco, P. E. Rouse, S. Chandrasekhar, T. A. J. Duke, W. B. Russel, W. D. Volkmuth, W. D. Volkmuth, Ö. Gaál   +17 more
core   +1 more source

The Staining of Proteins and Lipoids After Electrophoresis on Filter Paper [PDF]

, 1953
W. Loeffler, Ch. Wunderly
openalex   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Mechanism and in vivo evaluation :photodynamic antibacterial chemotherapy of lysine-porphyrin conjugate

Frontiers in Microbiology, 2016
We previously reported lysine-porphyrin conjugate 4i, which had potent photosensitive antibacterial effect on clinical isolated Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli (E. coli) and Pseudomonas aeruginosa (P.
Zengping eXu, Yuxiang eGao, Shuai eMeng, Shuai eMeng, Baochen eYang, Liyun ePang, Chen eWang, Tianjun eLiu   +7 more
doaj   +1 more source

An Apparatus for Paper Electrophoresis [PDF]

Journal of Clinical Pathology, 1955
G T, FRANGLEN, N H, MARTIN, J D, TREHERNE   +2 more
openaire   +2 more sources

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery

Advanced Science, EarlyView.
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo, Iwona Bernacka‐Wojcik, Lingkai Zhu, Marle E. J. Vleugels, Moa E. Hörberg, Caroline Lindholm, Magnus Berggren, Daniel T. Simon, Theresia Arbring Sjöström   +8 more
wiley   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

[Paper electrophoresis].

Il Progresso medico, 2003
J, GONZALEZ ALVAREZ, J, OTERO DE LA GANDARA, F E, DE SALAMANCA, C, ZUAZO DE LEON   +3 more
  +14 more sources