Results 171 to 180 of about 319,790 (256)

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara   +11 more
wiley   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li   +10 more
wiley   +1 more source

Performance and additional benefits of MALDI-TOF-MS in M-protein detection in plasma cell disorders. [PDF]

open access: yesAnn Med
Dong M   +11 more
europepmc   +1 more source

Pseudohyperphosphatemia in Multiple Myeloma: A Systematic Review of Case Reports and Case Series

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Pseudohyperphosphatemia (PHP) is a clinically significant laboratory artifact in patients with multiple myeloma (MM). It is often caused by paraprotein interference with phosphate assays. This systematic review summarizes reported cases, underlying mechanisms, and diagnostic approaches to distinguish spurious from true hyperphosphatemia.
Mahsa Dabir   +3 more
wiley   +1 more source

Mutation Spectrum of Hemoglobinopathies in Tunisia. [PDF]

open access: yesHum Mutat
Moumni I   +10 more
europepmc   +1 more source

Development and Analytical Validation of a Laboratory‐Customized TaqMan‐MGB Probe Method for CYP2C19 Genotyping

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A laboratory‐customized, open‐sequence TaqMan‐MGB probe assay was developed for detecting CYP2C19*2 and CYP2C19*17 polymorphisms using dried blood spot‐derived DNA. The assay demonstrated allele‐specific discrimination, candidate LODs of 1.17 × 102 copies/μL for CYP2C19*2 and 0.94 × 103 copies/μL for CYP2C19*17, and repeatability with CVs below 10%. In
Yaqun Liu   +7 more
wiley   +1 more source

Development and clinical validation of a multiplex visual POCT platform based on RT-RAA-CRISPR/Cas12a for porcine diarrheal viruses. [PDF]

open access: yesSynth Syst Biotechnol
Chen Y   +13 more
europepmc   +1 more source

Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright   +9 more
wiley   +1 more source

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