Results 141 to 150 of about 371,834 (316)

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Ketamine-Induced Uropathy: The Detrimental Effects of Chronic Ketamine Abuse Beyond the Bladder-A Case Report with a Brief Literature Review

Journal of Urological Surgery
Bladder toxicity associated with high-dose recreational ketamine use, is well-documented. However, the upper tract merits more attention because hydronephrosis may not solely stem from impaired bladder compliance and vesicoureteral reflux.
Eline Baetens, Diona D’Hondt, Werner Jacobs, Martin Lammens, Dan Wood, Gunter De Win   +5 more
doaj   +1 more source

Papillary Glioneuronal Tumor

Archives of Pathology & Laboratory Medicine, 2000
Abstract Tumors of mixed glioneuronal type are well recognized in the central nervous system. The most common examples of these lesions include gangliogliomas and dysembryoplastic neuroepithelial tumors. Recently, unusual examples of these lesions have been described, including the papillary glioneuronal tumor. This report describes a
openaire   +2 more sources

Papillary carcinoma in cervical cyst: primary tumor or metastasis?

, 2008
The cystic masses of the neck are usually benign lesions but they rarely may include malignancy or may be a metastasis of a carcinoma. Ectopic thyroid tissue is frequently seen on the tongue base, thyroglossal duct and around the thyroid gland itself ...
Samet Özlügedik, Ali Titiz, Müge Özcan, Adnan Ünal, Yavuz Fuat Yılmaz   +4 more
core   +1 more source

Human Fibroblast‐Myeloid cell tissue atlas across lung, synovium, skin and heart

Arthritis &Rheumatology, Accepted Article.
Background The availability of single‐cell RNA sequencing (scRNAseq data) in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Primary Pericardial Well-Differentiated Papillary Mesothelioma in a Spotted Hyena (Crocuta crocuta)

Veterinary Sciences
There have been few reports of neoplasia in hyenas to date. In this report, we describe a captive adult female spotted hyena (Crocuta crocuta) that developed inappetence, lethargy and marked abdominal distension over a 3-day period.
Louise van der Weyden, Dewald Keet, Nicolize O’Dell   +2 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Utilidad de la citología obtenida mediante aspiración con aguja fina en el diagnóstico de las neoplasias foliculares de la glándula tiroides en la E.S.E Hospital Universitario del Caribe: un estudio retrospectivo

Revista Colombiana de Cirugía
Introducción. En este estudio se evaluó en forma retrospectiva la utilidad de la citología obtenida mediante aspiración con aguja fina, en el diagnóstico de las neoplasias foliculares de la glándula tiroides. Metodología.
Francisco Herrera, Katherine Redondo, Carlos Osorio, Juan Grice, Alberto Fernández   +4 more
doaj  

Papillary Carcinoma of Lateral Thyroglossal Duct Cyst with De Novo Papillary Carcinoma of Thyroid: A Rare Case Report

Oman Medical Journal
Thyroglossal duct cysts are commonly seen in the midline of the neck, accounting for 7% of cases presenting with midline swelling. Carcinoma within a thyroglossal duct cyst is extremely rare, occurring in fewer than 1% of cases, and lateral occurrences ...
Tushar Kambale, Saurabh Shyamsunder Patil, Saloni Bhardwaj, Sirish Chandanwale   +3 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source