Results 101 to 110 of about 307,949 (334)

Tyrosine kinase inhibitors for the therapy of anaplastic thyroid cancer [PDF]

, 2015
Anaplastic thyroid cancer (ATC) is often incurable so new therapeutic approaches are needed. Tyrosine kinases inhibitors (such as imanitib, sunitinib or sorafenib) are under evaluation for the treatment of ATC.
Bond JA, Cohen EE, Dowlati A, Goulart B, Grande E, Hayashi N, Ibrahim N, Klopper JP, Mahlknecht U, Ohta K, Ruggeri RM, Sherman SI   +11 more
core   +1 more source

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Papillary lesions of the canine mammary gland: description and casuistry [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
The purpose of the study was to identify the casuistry of papillary mammary neoplasms in female dogs, describe their epidemiological (age, breed) and morphological characteristics, and determine the survival of patients.
M.C. Flecher, F. R. Souza, N.M. Avelar, T.C.M. Lopes, K.Y. R. Nakagaki, G.D. Cassali   +5 more
doaj   +1 more source

TERT Promoter Mutations in Papillary Thyroid Microcarcinomas [PDF]

, 2015
Small papillary thyroid carcinomas have contributed to the worldwide increased incidence of differentiated thyroid cancer observed over the past decades.
Bruno, Rocco, Casadei, Gianpaolo, Ciarrocchi, Alessia, Costante, Giuseppe, de Biase, Dario, Durante, Cosimo, Eszlinger, Markus, Filetti, Sebastiano, Frasoldati, Andrea, Gandolfi, Greta, Gugnoni, Mila, Paschke, Ralf, Pession, Annalisa, Piana, Simonetta, Ragazzi, Moira, Sancisi, Valentina, Tallini, Giovanni, Torlontano, Massimo, Visani, Michela   +18 more
core   +1 more source

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high‐grade serous ovarian carcinoma

International Journal of Cancer, EarlyView.
What's New? High‐grade serous ovarian carcinoma is often diagnosed at advanced stages due to non‐specific symptoms and the lack of reliable screening methods. This proof‐of‐concept study introduces a novel TP53 mutation panel using unique molecular identifier‐based next‐generation sequencing for sensitive detection of high‐grade serous ovarian ...
Amanda Olsson Widjaja, Peter Micallef, Maria Lycke, Tobias Österlund, Manuel Luna Santamaría, Julia Hedlund Lindberg, Therese Carlsson, Ulf Gyllensten, Anders Ståhlberg, Benjamin Ulfenborg, Anna Linder, Karin Sundfeldt   +11 more
wiley   +1 more source

Survival outcomes and prognostic factors of gastric carcinoma with neuroendocrine differentiation

International Journal of Cancer, EarlyView.
What's New? Although gastric carcinoma with neuroendocrine differentiation (GCNED) is associated with more aggressive features than conventional GC, its prognosis and survival remain poorly defined. To better understand survival patterns, the authors of the present study examined clinicopathological and prognostic features of GCNED patients following ...
Jinjin Li, Chenglong Wang, Yifan Shen, Zhen Huang, Jun Zhang, Siqi Rao, Youde Cao, Jiang Min   +7 more
wiley   +1 more source

Intracystic Papillary Carcinoma of the Breast: Report of Three Cases and Literature Review

Case Reports in Obstetrics and Gynecology, 2012
Intracystic papillary carcinoma is a rare malignant tumor of the breast. It occurs communally in postmenopausal women. Clinically it can be asymptomatic or manifested by a breast mass or a nipple discharge.
Yassir Ait Benkaddour, Sawsane El Hasnaoui, Karima Fichtali, Bouchra Fakhir, Hicham Jalal, Mouna Kouchani, Abderrahim Aboulfalah, Hassan Abbassi   +7 more
doaj   +1 more source

Artificial intelligence in cytopathology: A neural network to identify papillary carcinoma on thyroid fine-needle aspiration cytology smears

Journal of Pathology Informatics, 2018
Introduction: Fine-needle aspiration cytology (FNAC) for identification of papillary carcinoma thyroid is a moderately sensitive and specific modality. The present machine learning tools can correctly classify images into broad categories.
Parikshit Sanyal, Tanushri Mukherjee, Sanghita Barui, Avinash Das, Prabaha Gangopadhyay   +4 more
doaj   +1 more source

Concomitant Carcinoma in situ in Cystectomy Specimens Is Not Associated with Clinical Outcomes after Surgery [PDF]

, 2011
Objective: The aim of this study was to externally validate the prognostic value of concomitant urothelial carcinoma in situ (CIS) in radical cystectomy (RC) specimens using a large international cohort of bladder cancer patients. Methods: The records of
Colin P. Dinney, Derya Tilki, Eila Skinner, Francesco Montorsi, Giacomo Novara, Guru Sonpavde, Habuchi T, Hans-Martin Fritsche, Hendrik Isbarn, Jonathan I. Izawa, Knowles MA, Lamm DL, Patrick J. Bastian, Philipp Nuhn, Pierre I. Karakiewicz, Robert S. Svatek, Rosin MP, Sarkis AS, Shahrokh F. Shariat, Skinner DG, Spruck, Stefan C. Müller, Utz DC, Vincenzo Ficarra, Wassim Kassouf, Yves Fradet, Zincke H   +26 more
core   +1 more source

Papillary carcinoma of hyoid

International Journal of Surgery Case Reports, 2016
Thyroglosal duct cyst is a common anomaly with an incidence of 7% in adults, the rate of carcinoma in TGDC is 0.7-1.6%, and are extremely rare those originated in the hyoid bone.A 60 years old male patient, had a hard mass in the anterior neck. CT revealed a hyoid tumor.
López-Gómez, Javier, Salazar-Álvarez, Ma. Alejandra, Granados-Garcia, Martin   +2 more
openaire   +2 more sources