Results 201 to 210 of about 42,309 (293)

Acute cardiovascular changes following heat exposure during simulated shipboard firefighting

open access: yesExperimental Physiology, EarlyView.
Abstract Like structural firefighting, shipboard firefighting requires extreme exertion. However, shipboard firefighting may be a unique cardiovascular stress as most sailors lack extensive firefighting experience and may complete significant work before reaching the fire scene.
Daniel K. Sweet   +7 more
wiley   +1 more source

[Ca2+]i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium [PDF]

open access: yes, 2015
Acsai Károly   +9 more
core   +1 more source

Cardiopulmonary function in special operations forces compared to conventional infantry soldiers

open access: yesExperimental Physiology, EarlyView.
Abstract Fitness is essential to military personnel in general, especially in the special operations forces (SOF), where the demanding tasks require a high level of physical fitness and mental robustness. However, little research has been done on SOF to characterise the putative underlying cardiopulmonary adaptations that distinguish them from ...
Rasmus Syberg Rasmussen   +9 more
wiley   +1 more source

Strain‐based characterization of atrioventricular and left atrial remodelling in rat models of heart failure with preserved ejection fraction

open access: yesExperimental Physiology, EarlyView.
Abstract Current experimental models of heart failure with preserved ejection fraction (HFpEF) lack standardized approaches for evaluating left atrial (LA) remodelling and atrioventricular (AV) coupling, leaving a critical gap in mechanistic understanding and phenotypic characterization. This study aimed to explore LA function and AV coupling status in
Qingfeng Zhang   +4 more
wiley   +1 more source

Quantifying skin microvascular function responses to distinct forms of heat stress in humans using optical coherence tomography

open access: yesExperimental Physiology, EarlyView.
Abstract Optical coherence tomography (OCT) enables visualization and quantification of the cutaneous microvasculature, yet no study has compared responses to distinct forms of heating in humans. We hypothesized that local skin heating (LH) would evoke larger responses in microvascular diameter, velocity, flow and density than passive whole‐body ...
Kristanti W. Wigati   +5 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall   +8 more
wiley   +1 more source

Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we used mathematical modelling to explore the effect of diabetes on muscle mechanoenergetics. Our parameterisation of cross‐bridge models using data from non‐diabetic and diabetic human atrial tissues revealed lower values for cross‐bridge stiffness, detachment rates, attachment rates and lower ATP sensitivity in ...
Julia H. Musgrave   +4 more
wiley   +1 more source

Females exhibit greater cardiac volume reductions with expiratory muscle loading during submaximal exercise compared to males

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Intrathoracic pressure (ITP) manipulation during submaximal exercise reveals load‐ and sex‐specific cardiac volume responses. Inspiratory loading increased oesophageal pressure swings and the work of breathing (Wb) but did not alter stroke volume (SV) or ventricular volumes in males or females.
Sarah A. Angus   +6 more
wiley   +1 more source

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