Results 91 to 100 of about 92,917 (279)

Surgical Outcomes Following Neoadjuvant‐Targeted Therapy for Advanced Differentiated Thyroid Cancer—Real‐World Data

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman   +15 more
wiley   +1 more source

Concomitant clear cell renal cell carcinoma with osseous metaplasia and papillary thyroid microcarcinoma: a case report with literature review

open access: yesAfrican Journal of Urology, 2023
Backgrounds Although calcifications have been observed in various renal masses, osseous metaplasia has very rarely been reported. Here, we present a case of concomitant clear cell renal cell carcinoma with osseous metaplasia and papillary thyroid ...
Saman S. Fakhralddin   +8 more
doaj   +1 more source

Verruciform Xanthoma Within the Cyst Lining of Hidradenitis Suppurativa

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Verruciform xanthoma (VX) is a rare lesion most often seen in the oral mucosa or anogenital region, most commonly characterized histologically by verrucous epithelial hyperplasia and foamy histiocytes in the papillary dermis. While VX has been reported in association with inflammatory dermatoses such as lichen planus and lichen sclerosus, its ...
Deaquan Nichols   +4 more
wiley   +1 more source

Renal cell carcinoma in tuberous sclerosis complex [PDF]

open access: yes, 2014
Renal cell carcinoma (RCC) occurs in 2% to 4% of patients with tuberous sclerosis complex (TSC). Previous reports have noted a variety of histologic appearances in these cancers, but the full spectrum of morphologic and molecular features has not been ...
Cheng, Liang   +17 more
core   +1 more source

Clear cell papillary renal cell carcinoma: micro-RNA expression profiling and comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma [PDF]

open access: yesHuman Pathology, 2014
Clear cell papillary renal cell carcinoma (CCPRCC) is a low-grade renal neoplasm with morphological characteristics mimicking both clear cell renal cell carcinoma (CCRCC) and papillary renal cell carcinoma (PRCC). However, despite some overlapping features, their morphological, immunohistochemical, and molecular profiles are distinct.
Munari E   +10 more
openaire   +3 more sources

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Papillary renal cell carcinoma: what is missing in research? A case report and a review of literature

open access: yesSAGE Open Medical Case Reports, 2019
The incidence of renal cell carcinomas in adults ranges has been increasing over the past decades in both men and women. Once the incidence was 2.9%, now is reported to have increased to 3%–5% with male predominance according to the most recent reports ...
Ihab Eldessouki   +6 more
doaj   +1 more source

Identification of integrin drug targets for 17 solid tumor types. [PDF]

open access: yes, 2018
Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility.
Arun, Adith S   +2 more
core   +1 more source

Standardized Reporting of Microscopic Renal Tumor Margins: Introduction of the Renal Tumor Capsule Invasion Scoring System [PDF]

open access: yes, 2017
Purpose Renal tumor enucleation allows for maximal parenchymal preservation. Identifying pseudocapsule integrity is critically important in nephron sparing surgery by enucleation.
Boris, Ronald S.   +10 more
core   +1 more source

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