Results 111 to 120 of about 92,917 (279)

The spectrum of breast in situ papillary carcinomas with invasion and invasive breast carcinomas with papillary features: an overview of histological subtypes and diagnostic challenges

Histopathology, EarlyView.
Invasive breast carcinomas with papillary features (IBCP) comprise diverse subtypes with variable architecture, histopathology, and clinical behaviour. This review outlines evolving classification, diagnostic criteria, and treatment implications, highlighting challenges in distinguishing in situ from invasive lesions. Standardised diagnostic approaches
Emad A Rakha, Puay Hoon Tan, Wendy A Raymond   +2 more
wiley   +1 more source

ALK-rearranged renal cell carcinoma with gains of chromosomes 7 and 17q --- A case report

Urology Case Reports
ALK-rearranged renal cell carcinoma (ALK-RCC) is a rare subtype of RCC. In this report we describe the first ALK-RCC with gains of chromosome 7 and 17q. A 39-year-old male presented with an 11.5 cm renal mass and underwent a left radical nephrectomy. The
Muntha Chaudhari, Hafiz Anas Yahya, Jianming Pei, Gabriel J. DiNatale, Iryna Mahan, James Ryan Mark, Arthur S. Patchefsky, Matthew R. Zibelman, Shuanzeng Wei   +8 more
doaj   +1 more source

Hypoxic 3D in vitro culture models reveal distinct resistance processes to TKIs in renal cancer cells [PDF]

, 2012
The aim of this study is to determine the effect of hypoxia on axitinib and sorafenib-treated renal cell carcinoma (RCC) cells. Hypoxia is a crucial factor influencing transcription process via protein modulation, which was shown i.e.
Bielecka, Zofia, Malinowska, Agata, Brodaczewska, Klaudia, Klemba, Aleksandra, Kieda, Claudine, Krasowski, Paweł, Grzesiuk, Elzbieta, Piwowarski, Jan, Czarnecka, Anna, Szczylik, Cezary   +9 more
core   +6 more sources

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

International Journal of Dermatology, EarlyView.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla, Zseraldin Metyovinyi, Fanni Adél Meznerics, Arash Mirzahosseini, Judit Tőke, Miklós Tóth, Henriett Butz, Attila Patócs, Márta Medvecz   +8 more
wiley   +1 more source

Mapping of succinate dehydrogenase losses in 2258 epithelial neoplasms. [PDF]

, 2014
Losses in the succinate dehydrogenase (SDH) complex characterize 20% to 30% of extra-adrenal paragangliomas and 7% to 8% of gastric GISTs, and rare renal cell carcinomas.
Biernat, Wojciech, Czapiewski, Piotr, Langfort, Renata, Lasota, Jerzy, McCue, Peter, Miettinen, Markku, Sarlomo-Rikala, Maarit, Waloszczyk, Piotr, Wang, Zengfeng, Wazny, Krzysztof   +9 more
core   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

Interpretation of needle biopsies of the kidney for investigation of renal masses [PDF]

, 2018
The development of new therapeutic options for renal tumors has lead to the need of a pretherapeutic diagnosis for an increasing proportion of patients presenting with a renal mass. This need is particularly important for a small, incidentally discovered
de Leval, Laurence, Lhermitte, Benoît
core  

Gene amplification and overexpression of HER2 in renal cell carcinoma [PDF]

, 2002
Objective To determine the frequency of HER2 genetic abnormalities in renal cell carcinoma (RCC) and hence assess the potential suitability of Herceptin(TM) immunotherapy.
Aitchison, M., Bartlett, J.M.S., Latif, Z., Underwood, M.A., Watters, A.D.   +4 more
core   +2 more sources

Symptomatic Vulvar Primary Cutaneous Amyloidosis Associated With Low–Risk HPV: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Primary localized cutaneous amyloidosis (PCLA) of the vulva is an infrequent diagnosis. Its clinical presentation may mimic neoplastic or inflammatory lesions and could even be associated with human papillomavirus (HPV) of low or high oncogenic risk, making accurate diagnosis and exclusion of systemic involvement essential. A 73‐year‐old woman
Jorge Hoegl, Andreina Fernandes, Daniel Marquez, Ysleyer Silva   +3 more
wiley   +1 more source

Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2016
A multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination.
Jose Ignacio Lopez
doaj   +1 more source