Results 101 to 110 of about 14,159 (238)
Duplication of two distinct regions on chromosome 5Q in non-papillary renal-cell carcinomas [PDF]
Peter Bugert+2 more
openalex +1 more source
We report on three patients with Tuberous Sclerosis Complex (TSC) who had renal cell carcinomas with fibromyomatous stroma (RCC FMS), demonstrating a coexistent haemangioblastoma (HB)‐like morphology. Our findings support the conclusion that HB‐like features are part of the spectrum of RCC FMS with TSC/MTOR alterations.
Katherina Baranova+17 more
wiley +1 more source
Different sources of mutagenesis cause consistently identifiable patterns of mutations and mutational signatures that mirror the various carcinogenetic processes.
Peeter Karihtala+2 more
doaj
Prognostic models in papillary renal cell carcinoma [PDF]
A. Ari Hakimi+2 more
openaire +3 more sources
Tubulocystic carcinoma of kidney associated with papillary renal cell carcinoma
Tubulocystic renal cell carcinoma (TCRCC) is a rare variant of renal cell carcinoma, which has distinct histology but there is some controversy about its association with papillary renal cell carcinoma (PRCC) and cell of origin in literature. We report an 18-year-old girl with the rare TCRCC of kidney associated with PRCC with metastases to the para ...
Mahesh Deshmukh+3 more
openaire +4 more sources
PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer
ABSTRACT Alterations in the homologous recombination repair genes, such as BRCA1 and BRCA2, are prevalent in various cancers, presenting a unique opportunity to develop synthetic lethal strategies that target homologous recombination deficiency (HRD).
Yohei Okuda+8 more
wiley +1 more source
A distinct expression pattern and point mutation of c-kit in papillary renal cell carcinomas [PDF]
Zhen-Hua Lin+6 more
openalex +1 more source
ABSTRACT Objectives Immune checkpoint inhibitor (ICI)‐based combination therapies are first‐line treatments for locally advanced or metastatic renal cell carcinoma (mRCC). However, second‐line treatment efficacy remains uncertain due to limited large randomized trials. This study evaluated real‐world oncological outcomes after second‐line treatments in
Keita Nakane+8 more
wiley +1 more source
The genomic landscape of pediatric renal cell carcinomas
Summary: Pediatric renal cell carcinomas (RCC) differ from their adult counterparts not only in histologic subtypes but also in clinical characteristics and outcome. However, the underlying biology is still largely unclear.
Pengbo Beck+13 more
doaj
Molecular Genetic Evidence for the Independent Origin of Multifocal Papillary Tumors in Patients with Papillary Renal Cell Carcinomas [PDF]
Timothy D. Jones+12 more
openalex +1 more source