Results 41 to 50 of about 14,159 (238)
MET as a Target in Papillary Renal Cell Carcinoma [PDF]
Clinical Cancer Research, 2014 Abstract The biology underlying papillary renal cell carcinoma (pRCC) is largely unknown, and no specific therapies have been developed for advanced disease. The elucidation of the MET pathway status in types I and II pRCC may help to select patients who are more likely to benefit from MET inhibitors.
André P. Fay +3 more
openaire +3 more sources
Infectious Disease Reports, 2021 Neuropilin-1 (NRP1) is a recently identified glycoprotein that is an important host factor for SARS-CoV-2 infection. On the other hand, angiotensin-converting enzyme-2 (ACE2) acts as a receptor for SARS-CoV-2.
Md. Golzar Hossain +2 more
doaj +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
PLoS ONE, 2020 Renal cell carcinoma comprises a variety of entities, the most common being the clear-cell, papillary and chromophobe subtypes. These subtypes are related to different clinical evolution; however, most therapies have been developed for clear-cell ...
Lucía Trilla-Fuertes +13 more
doaj +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Diagnostic Potential of Multidetector Computed Tomography for Characterizing Small Renal Masses
The Scientific World Journal, 2015 Objectives. To assess the potential of CT for characterizing small renal tumors. Methods. 76 patients with
Maria Elisabetta Mancini +5 more
doaj +1 more source
Sub-typing of renal cell tumours; contribution of ancillary techniques
Diagnostic Pathology, 2009 Background Adult renal epithelial neoplasms are a heterogeneous group with varying prognosis and outcome requiring sub-classification. Methods Cases of renal cell carcinoma (RCC) in a 10 years period were analyzed with regard to the clinical features and
Singh Shrawan +4 more
doaj +1 more source
Kidney: Papillary renal cell carcinoma [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on Kidney: Papillary renal cell carcinoma, with data on clinics, and the genes involved.
openaire +2 more sources
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, EarlyView.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source
GOLPH2 expression in renal cell cancer
BMC Urology, 2008 Background Renal cell carcinomas (RCC) are among the most common and most lethal genitourinary malignancies. GOLPH2 (golgi phosphoprotein 2, GOLM1) has recently been proposed as a biomarker for hepatocellular and prostate cancer.
Jung Klaus +5 more
doaj +1 more source