Results 51 to 60 of about 14,159 (238)
High prevalence of p16 staining in malignant tumors.
PLoS ONE, 2022 p16 (CDKN2A) is a member of the INK4 class of cell cycle inhibitors, which is often dysregulated in cancer. However, the prevalence of p16 expression in different cancer types is controversial.
Noémi De Wispelaere +29 more
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Hereditary papillary renal cell carcinoma [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on Hereditary papillary renal cell carcinoma, with data on clinics, and the genes involved.
openaire +2 more sources
Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment
Advanced Therapeutics, EarlyView.How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley +1 more source
Histopathological review of renal pelvic tumours of Balkan nephropathy cases from Southern Serbia
Annals of Urologic Oncology, 2020 Background Urothelial tumour frequently associates with atrophied kidney pelvis in Balkan endemic nephropathy but histopathology illustration lacks both definition and immune profile for differential diagnosis from renal cell carcinoma.
Diana Herman +3 more
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Advanced Science, EarlyView.Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu +14 more
wiley +1 more source
Cellular Oncology, 2008 Background: A defective mitotic checkpoint has been proposed to contribute to chromosomal instability (CIN). We have previously shown that expression changes of the mitotic arrest deficiency (MAD) gene family plays a role in renal cell cancer (RCC ...
Mafalda Pinto +7 more
doaj +1 more source
Hereditary papillary renal cell carcinoma
Seminars in Diagnostic PathologyHereditary papillary renal cell carcinoma (HPRCC) is an autosomal dominant syndrome characterized by the occurrence of bilateral and multifocal, classic type papillary renal cell carcinomas. In the recent decades, extensive molecular studies have narrowed the molecular underpinnings of this syndrome to missense mutations in tyrosine kinase domain of ...
Isa Mulingbayan Jacoba, Zhichun Lu
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Papillary renal cell carcinoma: current and controversial issues
Current Opinion in Urology, 2022 Purpose of the review Papillary renal cell carcinoma (pRCC) is the second most frequent renal cancer subtype and represents 15–20% of all RCC. Classification of pRCC is changing because novel tumour entities have been discovered in the last years. In this review, we summarise recent studies relevant for the understanding of the
Angori, Silvia +2 more
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Advanced Science, EarlyView.This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu +7 more
wiley +1 more source
Localized abdominal wall metastasis of papillary renal cell carcinoma: a case report
Frontiers in SurgeryIntroductionPapillary renal cell carcinoma accounts for one tenth of all renal cell carcinomas. Compared to other renal cell carcinoma subtypes, it is more often localized at the time of diagnosis and rarely metastasizes to the skin.
Chadi Nahal +2 more
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