Results 71 to 80 of about 14,159 (238)

Robot‐Assisted Partial Nephrectomy for Multiple Synchronous Renal Tumors in Unilateral Kidney Using Hinotori Surgical System: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction Multiple synchronous renal tumors (MSRT) in unilateral kidney are clinically rare. Simultaneous resection for multiple tumors with RAPN is complicated and challenging. Herein, we report the successful resection of three synchronous renal tumors located in unilateral kidney with RAPN using the hinotori surgical robot system.
Kento Ozawa, Hiromitsu Watanabe, Kyohei Watanabe, Yuto Matsushita, Keita Tamura, Daisuke Motoyama, Atsushi Otsuka, Teruo Inamoto, Hideaki Miyake   +8 more
wiley   +1 more source

Efficacy and safety of CT-guided microwave ablation for stage T1a renal cell carcinoma in patients with a solitary kidney

International Journal of Hyperthermia, 2021
Objective To retrospectively evaluate early clinical outcomes of percutaneous microwave ablation (MWA) for stage T1a renal cell carcinomas (RCCs) in solitary kidney patients. Materials and methods 15 solitary kidney patients with 16 stage T1a N0M0 biopsy-
Hong Meng, Huan Yang, Haipeng Jia, Fengmin Pan, Xinzhe Dong, Bo Liu, Chunhai Li   +6 more
doaj   +1 more source

TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer

iMetaOmics, EarlyView.
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin, Kunhua Hu, Hongyan Sun, Xiaoqiong Bao, Lin Tang, Wei Liu, Zhixiang Zuo, Zhihang Chen   +7 more
wiley   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats.
Cristiane Gomes Fernandes Freire, Luana Aparecida Cunha, Mateus Andrade Stecca, Isabele Masson de Brito, Rafaella Riccio da Silva, Thiago Donizeth da Silva, Margarida Pereira Santos, Márcia Cristina Bizinotto de Assunção, Geraldo José Medeiros Fernandes, Evelise Aline Soares   +9 more
wiley   +1 more source

TGR5 expression in normal kidney and renal neoplasms

Diagnostic Pathology, 2018
Background The G protein-coupled bile acid receptor (TGR5) is a cell surface receptor which induces the production of intracellular cAMP and promotes epithelial-mesenchymal transition in gastric cancer cell lines.
Chaohui Lisa Zhao, Ali Amin, Yiang Hui, Dongfang Yang, Weibiao Cao   +4 more
doaj   +1 more source

Evaluation of renal masses with CEST MRI: Protocol optimization and preliminary results

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose This study investigates the application of CEST MRI in human kidneys, with the overarching goal of developing CEST MRI for renal mass characterization. Here, the focus is on the development of a protocol and the proof‐of‐principle evaluation of CEST for the characterization of clear cell renal cell carcinoma (ccRCC).
Xiaojing Wang, Jochen Keupp, Ivan E. Dimitrov, Ananth Madhuranthakam, Durga Udayakumar, Mahsa Taherzadeh, Emin Albayrak, Orson W. Moe, Payal Kapur, Robert E. Lenkinski, Ivan Pedrosa, Elena Vinogradov   +11 more
wiley   +1 more source

Nuclear Pedigree Criteria for the Identification of Individuals Suspected to be at Risk of an Inherited Predisposition to Renal Cancer

Hereditary Cancer in Clinical Practice, 2005
Renal clear cell carcinomas represent about 3% of all visceral cancers and account for approximately 85% of renal cancers in adults. Environmental and genetic factors are involved in the development of renal cancer.
Tołoczko-Grabarek Aleksandra, Sikorski Andrzej, Brzosko Marek, Lubiński Jan   +3 more
doaj   +1 more source

Malignancies and immunoglobulin G4‐related disease

Rheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

An atypical case of Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC)-associated renal cell carcinoma identified by next-generation sequencing

Human Pathology: Case Reports, 2018
Germline mutations in the fumarate hydratase (FH) gene classically lead to Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) syndrome. Patients with HLRCC typically exhibit multiple cutaneous and uterine leiomyomas at a young age. They also display
Daniel R. Matson, M.D., Ph.D., Molly A. Accola, Ph.D., William M. Rehrauer, Ph.D., Wei Huang, M.D.   +3 more
doaj