Results 101 to 110 of about 75,135 (288)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Role of Twist1 transcription factor in thyroid tumor progression [PDF]

open access: yes, 2011
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core  

Results of Surgical Treatment of Papillary Thyroid Cancer

open access: yesКлиническая и экспериментальная тиреоидология, 2014
Thyroid papillary cancer, one of the most frequent malignant tumors, aroused growing interest during last years due to continuous increase in number of such patients.

doaj   +1 more source

Papillary thyroid cancer in three children

open access: yesPediatric Endocrinology Diabetes and Metabolism, 2019
Thyroid cancers (TC) are rare diseases in the pediatric population and represents 0.5-3% of all malignant tumors in children. Differenti-ated thyroid cancer (DTC) is a major TC in children. Every patient under 18 years of age diagnosed with a thyroid nodule should under-go a detailed medical examination.
Justyna, Szmit-Domagalska   +5 more
openaire   +2 more sources

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

open access: yesMovement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard   +33 more
wiley   +1 more source

Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Develop a preoperative risk classifier for guiding the extent of surgery in differentiated thyroid carcinomas (DTCs) under 4 cm. Study Design In silico study, validation with retrospective cohort. Setting Genomic data repositories, academic tertiary medical center.
Thomas F. Barrett   +18 more
wiley   +1 more source

Unusual Presentation of Cystic Papillary Thyroid Carcinoma

open access: yesCase Reports in Endocrinology, 2012
Papillary thyroid carcinoma is the most common thyroid malignancy, accounting for 80% of all thyroid cancers. The most common presentation of thyroid cancer is an asymptomatic thyroid mass or a nodule.
Vijayraj S. Patil   +2 more
doaj   +1 more source

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

open access: yesThe Journal of Pathology, EarlyView.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal   +5 more
wiley   +1 more source

Anaplastic thyroid carcinoma: novel therapeutic targets and strategies [PDF]

open access: yes, 2008
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies, with a mean survival of only 6 months. Therefore, novel therapeutic approaches are desperately required. - dl1520 is a replication competent adenovirus that, due to lack
Libertini, Silvana
core  

Prospective external validation of ADNEX and RMI for estimating risk of malignancy in adnexal masses in general gynecological settings: Danish multicenter study

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives The primary aims of this study were to validate externally the diagnostic performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model for distinguishing between malignant and benign adnexal masses, when used by non‐expert ultrasound examiners in general gynecological settings with a low prevalence of ovarian ...
I. M. Dueholm Hjorth   +11 more
wiley   +1 more source

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