Results 211 to 220 of about 3,204,619 (291)

Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk

open access: yesOtolaryngology–Head and Neck Surgery, Volume 175, Issue 3, Page 578-586, September 2026.
Abstract Objective Develop a preoperative risk classifier for guiding the extent of surgery in differentiated thyroid carcinomas (DTCs) under 4 cm. Study Design In silico study, validation with retrospective cohort. Setting Genomic data repositories, academic tertiary medical center.
Thomas F. Barrett   +18 more
wiley   +1 more source

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

open access: yesThe Journal of Pathology, Volume 270, Issue 1, Page 4-22, September 2026.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal   +5 more
wiley   +1 more source

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang   +4 more
wiley   +1 more source

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

open access: yesThe Journal of Dermatology, Volume 53, Issue 9, Page 1245-1260, September 2026.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe   +4 more
wiley   +1 more source

circMAN1A2 as an Isoform‐Resolved Circular RNA Hub in Cancer

open access: yesCancer Science, Volume 117, Issue 9, Page 2345-2356, September 2026.
circMAN1A2 as an isoform‐resolved circular RNA hub in cancer. circMAN1A2 is generated by back‐splicing of MAN1A2 pre‐mRNA, with alternative circularization producing multiple isoforms, including the predominant circMAN1A2(2–5). Its mechanistic interfaces include miRNA‐associated regulation, RBP binding/proteostasis control, BSJ‐mediated RNA–RNA pairing,
Hanyu Shang   +4 more
wiley   +1 more source

MAPK13 promotes the progression of papillary thyroid cancer. [PDF]

open access: yesEur Thyroid J
Zhao R   +9 more
europepmc   +1 more source

APOC1‐Associated VLDL‐Pathway Dysregulation in Papillary Thyroid Carcinoma: A Reproducible Cross‐Cohort Transcriptomic Signature Associated With the Diagnostic‐to‐Treatment Interval

open access: yesChemical Biology &Drug Design, Volume 108, Issue 3, September 2026.
Across four independent thyroid cancer cohorts, multi‐omics analysis identifies a reproducible APOC1–LPL–VLDLR lipid‐pathway signature linked to the preoperative diagnostic‐to‐treatment interval, nominating triglyceride‐rich lipoprotein metabolism as a candidate window for monitoring and a potential metabolic axis in papillary thyroid carcinoma ...
Yinfeng Li   +4 more
wiley   +1 more source

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