Results 181 to 190 of about 186,793 (334)
Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song+9 more
wiley +1 more source
BMP signalling in colorectal cancer: losing the yin to WNTs yang
Abstract Colorectal cancer (CRC) is the third most common form of cancer globally, and arises from the hyperproliferation of epithelial cells in the intestine. The architecture and maintenance of these cells is governed by two major signalling pathways working in a counter‐gradient: the stem cell WNT signalling pathway, and the prodifferentiation bone ...
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
A Case of Occult Papillary Carcinoma of Thyroid, Invaded Trachea and Esophagus [PDF]
Deok Su Cho+6 more
openalex +1 more source
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe+7 more
wiley +1 more source
Papillary Carcinoma of the Thyroid Arising from Dyshormonogenetic Goiter.
Tohru Yashiro+7 more
openalex +2 more sources
Current trends in the management of well differentiated papillary thyroid carcinoma. [PDF]
Barbara Solomon+2 more
openalex +1 more source
Total thyroidectomy without prophylactic central neck dissection in clinically node-negative papillary thyroid cancer: is it an adequate treatment? [PDF]
CALO', PIETRO GIORGIO+6 more
core +1 more source
We established a novel patient‐derived BRAF V600E‐mutated lung adenocarcinoma cell line and demonstrated that combining a novel TEAD1 inhibitor (VT103) with dabrafenib enhances therapeutic efficacy through survivin downregulation. Our tissue microarray analysis revealed a strong correlation between YAP1, TEAD1, and survivin expression in lung ...
Kazutaka Hosoya+19 more
wiley +1 more source