Results 231 to 240 of about 150,574 (342)

Does a Restrictive Diagnostic Work‐up for Thyroid Nodules Lead to a Different Papillary Thyroid Cancer Patient Population? A Comparison Between Dutch and U.S. T1‐T3 Patient Population

open access: yesWorld Journal of Surgery, Volume 49, Issue 4, Page 985-996, April 2025.
Does a restrictive diagnostic work‐up for thyroid nodules lead to a different papillary thyroid cancer patient population? A comparison between Dutch and U.S. PT1–T3 patient population. Abstract Introduction The 2015 American Thyroid Association guidelines recommend de‐escalating surgical treatment for papillary thyroid cancer (PTC).
Maaike B. C. ten Hoor   +9 more
wiley   +1 more source

Papillary thyroid carcinoma

open access: yesRadiopaedia.org, 2020
F. Limaiem, A. Rehman, Thomas Mazzoni
semanticscholar   +1 more source

Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1109-1120, April 2025.
Summary Germline variants in DDX41 (DDX41MT‐germline predisposition syndrome [GPS]) are associated with predisposition to haematological malignancies (HM), including lymphoid and myeloid neoplasms (MN). We retrospectively analysed the clinical and molecular features of 195 patients diagnosed and treated at Mayo Clinic with DDX41MT‐GPS.
Yael Kusne   +16 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 7, Page 1416-1445, April 2025.
Abstract In the past year, the European Medicines Agency (EMA), the Food and Drug Administration (FDA) and the Medicines and Healthcare Products Regulatory Agency (MHRA) authorised 53 novel drugs. While the 2024 harvest is not as rich as in 2023, when 70 new chemical entities were approved, the number of ‘orphan’ drug authorisations in 2024 (21) is ...
Stavros Topouzis   +16 more
wiley   +1 more source

CYP24A1 Binding to FUS Maintains Tumor Properties by Regulating the miR‐200c/ZEB1/EMT Axis

open access: yesCancer Science, Volume 116, Issue 4, Page 910-922, April 2025.
The active vitamin D‐degrading enzyme (CYP24A1) is a potential oncogene in ovarian and lung cancer. Mechanically, 87–297 amino acid motif of CYP24A1 bound specifically to FUS protein, consequentially reducing FUS affinity for miR‐200c. A reduction in miR‐200c levels resulted in a significant activation of its target gene ZEB1, thereby facilitating the ...
Ping Wang   +8 more
wiley   +1 more source

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