Results 21 to 30 of about 150,574 (342)

Evaluation of the Pharmacokinetic Drug Interaction of Capmatinib With Itraconazole and Rifampicin and Potential Impact on Renal Transporters in Healthy Subjects

The Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 228-238, February 2023., 2023
Abstract Capmatinib is a highly specific, potent, and selective mesenchymal–epithelial transition factor inhibitor predominantly eliminated by cytochrome P450 (CYP) 3A4 and aldehyde oxidase. Here, we investigated the effects of a strong CYP3A inhibitor (itraconazole) and a strong CYP3A inducer (rifampicin) on single‐dose pharmacokinetics of capmatinib.
Xiaoming Cui, Xinhui Chen, Nathalie Pognan, Tirtha Sengupta, Gholamreza Rahmanzadeh, Ruediger Kornberger, Monica Giovannini   +6 more
wiley   +1 more source

Papillary Thyroid Carcinoma

The American Journal of Surgical Pathology, 2003
Papillary thyroid cancer is after ovarian cancer the most frequent malignant disease of the endocrine system and because of this fact, early detection and appropriate surgical treatment is essential. Radical surgical treatment lower the risk of the disease relapse and postoperative adjuvant therapy with radio iodine is possible as well as postoperative
C. Francesco, BRANDI, MARIA LUISA, TONELLI, FRANCESCO, M. Zuckermann, A. Cariati   +4 more
openaire   +6 more sources

Machine learning using convolutional neural networks for SERS analysis of biomarkers in medical diagnostics

Journal of Raman Spectroscopy, Volume 53, Issue 12, Page 2044-2057, December 2022., 2022
We compared the performances of spectral decomposition, support vector regression, random forest regression, partial least squares regression, and convolutional neural network for SERS “spectral unmixing” from a multiplexed mixture of 7 SERS‐active “nanorattles” loaded with different dyes for mRNA biomarker detection.
Joy Qiaoyi Li, Priya Vohra Dukes, Walter Lee, Michael Sarkis, Tuan Vo‐Dinh   +4 more
wiley   +1 more source

Papillary Thyroid Carcinoma Presenting with a Right Preauricular and Intracranial Mass

Philippine Journal of Otolaryngology Head and Neck Surgery, 2010
Objective: To describe a case of a papillary thyroid carcinoma presenting with a pre-auricular and an intracranial mass and review the literature on the metastatic nature and invasiveness of papillary thyroid carcinoma.
Renato C. Pascual, Johann F. Castañeda, Joel A. Romualdez   +2 more
doaj   +1 more source

Active Surveillance for T1bN0M0 Papillary Thyroid Carcinoma.

Thyroid, 2019
BACKGROUND Prospective trials of active surveillance for asymptomatic papillary microcarcinoma (T1aN0M0) since the 1990s have shown progression rates of only 5-10%.
T. Sakai, I. Sugitani, A. Ebina, Osamu Fukuoka, Kazuhisa Toda, H. Mitani, Keiko Yamada   +6 more
semanticscholar   +1 more source

Papillary Thyroid Carcinoma

Journal of Thyroid Disorders & Therapy, 2014
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy, accounting for 80 % of thyroid carcinomas in adults and 90 % in children. PTC is a malignant epithelial tumor showing follicular differentiation and distinctive nuclear features. Patients usually are 20–50 years old, but those of any age may be affected.
Abhiseck Chaudary, Ameer Afzal, Asad Azim, Khwaja M. Azim, Khalid Masud Alam, Hafiz Mohammad Asif Maqboo, Ashfaq Ahmed, Tooba Mahmud Gauhar   +7 more
  +6 more sources

Simultaneous occurrence of medullary and papillary thyroid microcarcinomas: a case series and review of the literature

Journal of Medical Case Reports, 2013
Introduction Papillary thyroid microcarcinoma has been demonstrated to present in association with medullary thyroid carcinoma, however, medullary thyroid carcinoma and papillary thyroid carcinoma represent rare entities.
Adnan Zaina, Arad Eldad, Dana James, Shendler Yaakov, Baron Elzbieta   +4 more
doaj   +1 more source

NephroNet: A Novel Program for Identifying Renal Cell Carcinoma and Generating Synthetic Training Images with Convolutional Neural Networks and Diffusion Models [PDF]

, 2023
Renal cell carcinoma (RCC) is a type of cancer that originates in the kidneys and is the most common type of kidney cancer in adults. It can be classified into several subtypes, including clear cell RCC, papillary RCC, and chromophobe RCC. In this study, an artificial intelligence model was developed and trained for classifying different subtypes of ...
arxiv   +1 more source

BRAF in Papillary Thyroid Carcinoma

Analytical Cellular Pathology, 2007
Novel genetic findings about papillary thyroid carcinoma identify BRAF gene as a subject of great interest. Involvement of BRAF gene in pathogenesis of PTC, diagnostic value and the putative prognostic significance of its T1799A mutation are summarized in this article.
Angelo Paradiso, Salvatore Giovanni Lanzilotta, Gianni Simone, Luciano Grammatica   +3 more
openaire   +4 more sources

Prediction of Lymph Node Metastasis in Patients With Papillary Thyroid Carcinoma: A Radiomics Method Based on Preoperative Ultrasound Images

Technology in Cancer Research and Treatment, 2019
Background: Papillary thyroid carcinoma is a type of indolent tumor with a dramatically increasing incidence rate and stably high survival rate. Reducing the overdiagnosis and overtreatment of papillary thyroid carcinoma is clinically emergent and ...
Tongtong Liu, Shichong Zhou, Jinhua Yu, Yi Guo, Yuanyuan Wang, Jin Zhou, Cai Chang   +6 more
semanticscholar   +1 more source