Results 41 to 50 of about 152,043 (303)

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Metastatic Papillary Thyroid Carcinoma with Multifocal Synchronous Transformation to Anaplastic Thyroid Carcinoma

open access: yesCase Reports in Pathology, 2016
Papillary thyroid carcinoma is a common malignancy to affect the thyroid and is typified by a nonaggressive nature and low rates of mortality. In contrast, anaplastic thyroid carcinoma is the most aggressive thyroid malignancy with a mortality rate of ...
Mark Benedict, Jose Costa
doaj   +1 more source

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

open access: yesAdvanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang   +11 more
wiley   +1 more source

Thyroid hemangioma and concurrent papillary thyroid carcinoma

open access: yesOtolaryngology Case Reports, 2021
Background: Hemangiomas are benign vascular neoplasms resulting from abnormal vascular proliferation. Thyroid hemangiomas are rare occurrences with only 33 cases reported in the literature.
Robert T. Cristel   +6 more
doaj  

Immunohistochemistry on cell blocks a method for pre-operative diagnosis of papillary thyroid carcinoma by FNAC

open access: yesمجلة كلية الطب, 2018
Background: Papillary thyroid carcinoma (PTC) is the commonest thyroid cancer. Cases in category- 5a of Bethesda system (suspicious for papillary carcinoma) are treated by surgical lobectomy followed by total thyroidectomy if histopathology confirms ...
Hussain A. Aljebori
doaj   +1 more source

Thyroid Carcinoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.

open access: yesThe Journal of the National Comprehensive Cancer Network, 2022
Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation (iodine-131) in select patients and thyroxine therapy in most ...
R. Haddad   +35 more
semanticscholar   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

open access: yesAdvanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu   +12 more
wiley   +1 more source

Comparison of DNA Changes in the Genomes of Thyroid Hyperplasia, Papillary Thyroid Carcinoma, and Healthy Tissues Using Random Amplified Polymorphic DNA Polymerase Chain Reaction

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Background: Thyroid carcinoma is the most common endocrine cancer. There are several methods for determining the mutation of genes, one of them is random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR).
Ardeshir Talebi   +3 more
doaj   +1 more source

Papillary Thyroid Carcinoma: An Overview [PDF]

open access: yesArchives of Pathology & Laboratory Medicine, 2006
Abstract Papillary carcinoma is the most common malignant tumor of the thyroid. It has a variable macroscopic appearance that differs according to the variant microscopic morphologies and the presence or absence of degenerative changes. The histologic variants can be challenging to the pathologist, and some are of clinical significance ...
Sylvia L. Asa, Nabeel Al-Brahim
openaire   +2 more sources

miR-214 regulates papillary thyroid carcinoma cell proliferation and metastasis by targeting PSMD10

open access: yesInternational Journal of Molecular Medicine, 2018
MicroRNAs (miRNAs) have important effects on cancer occurrence and development by adjusting gene expression. The aim of the present study was to examine the role of miR-214 in papillary thyroid carcinoma cell proliferation and metastasis, and its ...
Fang-zhou Liu   +8 more
semanticscholar   +1 more source

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