Results 41 to 50 of about 152,043 (303)
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Papillary thyroid carcinoma is a common malignancy to affect the thyroid and is typified by a nonaggressive nature and low rates of mortality. In contrast, anaplastic thyroid carcinoma is the most aggressive thyroid malignancy with a mortality rate of ...
Mark Benedict, Jose Costa
doaj +1 more source
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang+11 more
wiley +1 more source
Thyroid hemangioma and concurrent papillary thyroid carcinoma
Background: Hemangiomas are benign vascular neoplasms resulting from abnormal vascular proliferation. Thyroid hemangiomas are rare occurrences with only 33 cases reported in the literature.
Robert T. Cristel+6 more
doaj
Background: Papillary thyroid carcinoma (PTC) is the commonest thyroid cancer. Cases in category- 5a of Bethesda system (suspicious for papillary carcinoma) are treated by surgical lobectomy followed by total thyroidectomy if histopathology confirms ...
Hussain A. Aljebori
doaj +1 more source
Thyroid Carcinoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation (iodine-131) in select patients and thyroxine therapy in most ...
R. Haddad+35 more
semanticscholar +1 more source
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu+12 more
wiley +1 more source
Background: Thyroid carcinoma is the most common endocrine cancer. There are several methods for determining the mutation of genes, one of them is random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR).
Ardeshir Talebi+3 more
doaj +1 more source
Papillary Thyroid Carcinoma: An Overview [PDF]
Abstract Papillary carcinoma is the most common malignant tumor of the thyroid. It has a variable macroscopic appearance that differs according to the variant microscopic morphologies and the presence or absence of degenerative changes. The histologic variants can be challenging to the pathologist, and some are of clinical significance ...
Sylvia L. Asa, Nabeel Al-Brahim
openaire +2 more sources
miR-214 regulates papillary thyroid carcinoma cell proliferation and metastasis by targeting PSMD10
MicroRNAs (miRNAs) have important effects on cancer occurrence and development by adjusting gene expression. The aim of the present study was to examine the role of miR-214 in papillary thyroid carcinoma cell proliferation and metastasis, and its ...
Fang-zhou Liu+8 more
semanticscholar +1 more source