Results 61 to 70 of about 150,574 (342)
STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken+3 more
wiley +1 more source
Papillary thyroid carcinoma is a common malignancy to affect the thyroid and is typified by a nonaggressive nature and low rates of mortality. In contrast, anaplastic thyroid carcinoma is the most aggressive thyroid malignancy with a mortality rate of ...
Mark Benedict, Jose Costa
doaj +1 more source
Papillary thyroid carcinoma is the most common form of thyroid cancer and is usually associated with a good outcome. However, there are some aggressive variants wherein the prognosis may not be as good as for a conventional papillary thyroid carcinoma ...
P K Pravanya+4 more
doaj +1 more source
A Robust Deep Learning Method with Uncertainty Estimation for the Pathological Classification of Renal Cell Carcinoma based on CT Images [PDF]
Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC) based on CT images.
arxiv
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu+12 more
wiley +1 more source
Thyroid hemangioma and concurrent papillary thyroid carcinoma
Background: Hemangiomas are benign vascular neoplasms resulting from abnormal vascular proliferation. Thyroid hemangiomas are rare occurrences with only 33 cases reported in the literature.
Robert T. Cristel+6 more
doaj
NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States
An increase in thyroid cancers, predominantly papillary thyroid carcinoma (PTC), has been recently reported in children.
M. Prasad+11 more
semanticscholar +1 more source
Wang et al. discover a novel lncRNA regulator of mutant oncoprotein which prevents AKT1E17K dephosphorylation. SVIL‐AS1 overexpression correlates with poor prognosis of breast cancer patients. It interacts with AKT1E17K protein and impedes PP2A holoenzyme from dephosphorylating AKT1 by blocking the binding of the regulatory subunit PPP2R2A to AKT1 ...
Jingyi Wang+8 more
wiley +1 more source
Abstract Introduction Paediatric AML patients with hyperleukocytosis have a poor prognosis and higher early mortality. Therefore, more studies are needed to explore relevant prognostic indicators and develop effective prevention strategies for this type of childhood AML. Methods All original data were obtained from the TARGET database.
Nan Mei+6 more
wiley +1 more source
Huge posterior triangle lymphadenopathy as a rare sole presentation of papillary thyroid carcinoma
Papillary thyroid carcinoma is well-known for its low malignant potential with good prognostic outcome. It usually presents as a palpable thyroid mass but scarcely manifests as an isolated cervical lymphadenopathy. A 50-year-old man presented with a huge
Don Evana Ezrien+6 more
doaj +1 more source