Phylogeny and latitudinal biogeography of the Papillomaviridae Family [PDF]
Introduction: The latitudinal diversity gradient (LDG), a fundamental ecology pattern for higher organisms, has explained the increase of species diversity from the poles towards the tropics. Can we explain the biodiversity of Papillomaviruses based on this pattern?
Marlon S. Zambrano-Mila+2 more
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ICTV Virus Taxonomy Profile: Papillomaviridae [PDF]
The Papillomaviridae is a family of small, non-enveloped viruses with double-stranded DNA genomes of 5 748 to 8 607 bp. Their classification is based on pairwise nucleotide sequence identity across the L1 open reading frame. Members of the Papillomaviridae primarily infect mucosal and keratinised epithelia, and have been isolated from fish, reptiles ...
Koenraad Van Doorslaer+10 more
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Detection of the prototype of a potential novel genus in the family Papillomaviridae in association with canine epidermodysplasia verruciformis [PDF]
Epidermodysplasia verruciformis (EV) is a rare human genetic predisposition to develop flat warts, some of which subsequently undergo cancer transformation. Some human papillomaviruses (HPVs), i.e. HPV 5 and 8, have been associated with cancer development as a sequela of EV.
Kurt Tobler+3 more
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Evolution of the Papillomaviridae
Viruses belonging to the Papillomaviridae family have been isolated from a variety of mammals, birds and non-avian reptiles. It is likely that most, if not all, amniotes carry a broad array of viral types. To date, the complete genomic sequence of more than 240 distinct viral types has been characterized at the nucleotide level.
Koenraad Van Doorslaer
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Evidence for a Structural Relationship between BRCT Domains and the Helicase Domains of the Replication Initiators Encoded by thePolyomaviridaeandPapillomaviridaeFamilies of DNA Tumor Viruses [PDF]
ABSTRACTStudies of DNA tumor viruses have provided important insights into fundamental cellular processes and oncogenic transformation. They have revealed, for example, that upon expression of virally encoded proteins, cellular pathways involved in DNA repair and cell cycle control are disrupted.
Anuradha Kumar+5 more
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New insights into Sauropsid Papillomaviridae evolution and epizootiology: discovery of two novel papillomaviruses in native and invasive Island geckos [PDF]
Abstract Papillomaviruses cause persistent infections in skin and mucosal membranes and, in at least one species, are also be able to infect a tissue of mesenchymal origin. Infections may either be subclinical or induce proliferative lesions.
Jessica E. Agius+3 more
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Introduction. High carcinogenic-risk human papillomaviruses (hrHPVs) are recognized as etiological agents of cervical cancer. Constant expression of the viral oncoproteins, E6 and E7, is required for maintenance of the malignant phenotype of tumor cells.
N. P. Kisseljova+8 more
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A Novel Virus Detected in Papillomas and Carcinomas of the Endangered Western Barred Bandicoot ( Perameles bougainville ) Exhibits Genomic Features of both the Papillomaviridae and Polyomaviridae [PDF]
ABSTRACT Conservation efforts to prevent the extinction of the endangered western barred bandicoot ( Perameles bougainville ) are currently hindered by a progressively debilitating cutaneous and mucocutaneous papillomatosis and carcinomatosis syndrome observed in captive and wild populations. In this study,
Lucy Woolford+9 more
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Introduction. Human papillomavirus (HPV) of high carcinogenic risk (HCR), in addition to being the etiological agent of cervical cancer, also contribute to development of cancer of the anus, vagina, penis, vulva and oropharyngeal cancer. In this connection, further study of the biological properties of this agent and its prevalence in different ...
А. А. Попова+4 more
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Phylogenetic analysis of novel dolphin (Tursiops truncatus) papillomavirus sequences, TtPV1, -2, and -3, indicates that the early and late protein coding regions of their genomes differ in evolutionary history. Sliding window bootscan analysis showed a significant a change in phylogenetic clustering, in which the grouped sequences of TtPV1 and -3 move ...
Annabel Rector+12 more
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