Results 321 to 330 of about 3,290,822 (384)
Angewandte Chemie, Volume 137, Issue 32, August 4, 2025.To monitor small molecule‐induced changes in protein polyubiquitination in an unbiased manner, we employ enrichment through tandem ubiquitin binding entities coupled to LC‐MS/MS analysis (TUBE‐MS). By applying the workflow to PROTAC, p97‐ and deubiquitinase‐inhibitor treatment of cells, we demonstrate its broad applicability and reveal the induction of
Siska Führer +6 more
wiley +2 more sources
MedComm – Oncology, Volume 4, Issue 3, September 2025.Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun +10 more
wiley +1 more source
Public Health Challenges, Volume 4, Issue 3, September 2025.ABSTRACT Background Cervical cancer is one of the common cancer among women worldwide, with high mortality and morbidity rates. The human papillomavirus (HPV) vaccine is one of several preventative options for cervical cancer. The HPV vaccine is just introduced in Nepal and is still not included in the national immunization schedule.
Radha Devi Dhakal +3 more
wiley +1 more source
International Journal of Cancer, Volume 157, Issue 4, Page 627-633, 15 August 2025.What's new? Cervical cancer incidence in the Netherlands is increasing among women in younger birth cohorts. This raises concerns about the start and end ages of the country's human papillomavirus (HPV) screening program, which currently includes women ages 30 to 60.
Sylvia Kaljouw +3 more
wiley +1 more source
The population-level impact of bivalent HPV vaccination on closely related non-vaccine types [PDF]
, 2018 Kavanagh, Kimberly +2 more
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Advanced Science, Volume 12, Issue 29, August 7, 2025.Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao +6 more
wiley +1 more source
Oncogenic Human Papillomavirus Infection and Cervical Lesions in Aboriginal Women of Nunavut, Canada
, 2001 Sylvia Healey +6 more
openalex +1 more source
Recent Advances in mRNA Delivery Systems for Cancer Therapy
Advanced Science, Volume 12, Issue 29, August 7, 2025.This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang +9 more
wiley +1 more source