Intra-epithelial vaccination with COPV L1 DNA by particle-mediated DNA delivery protects against mucosal challenge with infectious COPV in beagle dogs. [PDF]
Protection against viral challenge with canine oral papillomavirus (COPV) was achieved by immunisation via particle-mediated DNA delivery (PMDD) of a plasmid encoding the COPV L1 gene to cutaneous and oral mucosal sites in beagle dogs.
Walcott, S. +7 more
core
A qualitative study of HPV vaccine acceptability among health workers, teachers, parents, female pupils, and religious leaders in northwest Tanzania [PDF]
Background As human papillomavirus (HPV) vaccines become available in developing countries, acceptability studies can help to better understand potential barriers and facilitators of HPV vaccination and guide immunisation programs. Methods Prior
Hayes, R.J. +17 more
core +1 more source
Rethinking the tumor microbiome: Methodological challenges and a framework for rigorous research
Abstract The intratumoral microbiome, as an essential component of the tumor microenvironment, has attracted increasing attention in recent years. The tumor microbiota displays an intricate interplay with its biological behaviors. However, emerging controversies, including the retraction of Poore et al.'s article, highlight significant challenges ...
Lingxuan Zhu +13 more
wiley +1 more source
Nucleic acid vaccines for human papillomavirus; prevention or treatment [PDF]
Introduction: Cervical cancer is the fourth common cancer among women. In almost all cases of this cancer, infection to a high risk human papilloma virus (HPV) especially type 16 and 18 is observed.
Solmaz Moniri Javadhesari +2 more
doaj +1 more source
Cervical human papillomavirus infection and squamous intraepithelial lesions in rural Gambia, West Africa: viral sequence analysis and epidemiology. [PDF]
The development of effective strategies against cervical cancer in Africa requires accurate type specific data on human papillomavirus (HPV) prevalence, including determination of DNA sequences in order to maximise local vaccine efficacy.
Gelder, CM +32 more
core +1 more source
ABSTRACT Objective To compare the predictive performance of cytology and high‐risk HPV (hrHPV) testing in young HPV‐vaccinated women participating in the cervical screening programme in Scotland. Design Prospective observational study. Setting Routine cervical screening services in three Scottish Health Boards between 2011 and 2015.
Margaret E. Cruickshank +8 more
wiley +1 more source
BACKGROUND: Human papillomavirus (HPV) is a large family of viruses and is considered the most common sexually transmitted infection. One of the effective and cost-effective primary prevention methods are vaccines made against the HPV.
Leila Shasti +5 more
doaj +1 more source
Outcomes and Trends of Anal Squamous Cell Carcinoma in Queensland: A 26‐Year Review
Anal squamous cell carcinoma incidence and mortality increased substantially in Queensland over 26 years, while survival outcomes remained unchanged. Evolving HPV prevention and screening strategies offer opportunities to reduce future disease burden, but substantial implementation barriers exist.
Amanda G. Liesegang +3 more
wiley +1 more source
Human Papillomavirus-Related Cancer Vaccine Strategies
Background: Human papillomavirus (HPV) persistent infection is a major pathogenic factor for HPV-related cancers, such as cervical cancer (CC), vaginal cancer, vulvar cancer, anal cancer, penile cancer, and head and neck cancer (HNC).
Ling Xu, Xia Cai
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source

