Results 231 to 240 of about 1,550,416 (278)
Photocatalytic cross‐coupling: A redox‐neutral photochemical method enables direct C(sp2)─C(sp2) bond formation between phenols and heteroaryl halides using an organic dye and base. Complementary radical generation allows efficient cross‐coupling in up to 91% yield. Mechanistic studies, DFT, HTE, and machine learning rationalize and predict reactivity,
Matthew C. Carson +4 more
wiley +1 more source
One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra +8 more
wiley +1 more source
Translation, cross-cultural adaptation, and validation of the Integrated Palliative Care Outcome Scale Renal (IPOS-Renal) for Brazilian Portuguese. [PDF]
Trindade MAD +2 more
europepmc +1 more source
[Correlation of occlusion pressure with sedation in non-neurocritical patients]. [PDF]
Valadez-Andrade JA +3 more
europepmc +1 more source
Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp +29 more
wiley +1 more source

