Results 31 to 40 of about 1,550,416 (278)
A New Genus of Miniaturized and Pug-Nosed Gecko from South America (Sphaerodactylidae: Gekkota) [PDF]
, 2011 Sphaerodactyl geckos comprise five genera distributed across Central and South America and the Caribbean. We estimated phylogenetic relationships among sphaerodactyl genera using both separate and combined analyses of seven nuclear genes.
Bauer, Aaron M. +4 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Journal of Threatened Taxa, 2017 Fifteen Lowland Tapirs Tapirus terrestris were found road killed between kilometer six and 76 of the BR-163 highway, in the state of Pará, Brazil. The findings took place during two periods, May/July 2016, and June 2017. This highway is internationally
Marco A. de Freitas +4 more
doaj +1 more source
Interação de fatores biofísicos e do uso da terra da dinâmica da paisagem do município de Ourém, Pará, em sistema de informação geográfica. [PDF]
, 2016 bitstream/item/61286/1/CPATU-Doc133.pdfAnexo 3 mapas: Carta de aptidão agrícola do Município de Ourém ? Pará; Carta de solos do Município de Ourém ?
ROCHA, A. M. A. da +3 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Desenvolvimento e Meio Ambiente, 2019 The historical environmental problems in the Amazon urge greater governance and transparency at the municipal level. The decentralizing of municipal environmental management (MEM) is an ongoing process in the Brazilian Amazonbut a monitoring mechanism is
Benedito Evandro Barros da Silva +2 more
doaj +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
"Modelling Sustainable International Tourism Demand to the Brazilian Amazon" [PDF]
The Amazon rainforest is one of the world's greatest natural wonders and holds great importance and significance for the world's environmental balance. Around 60% of the Amazon rainforest is located in the Brazilian territory.
Jose Angelo Divino, Michael McAleer
core +6 more sources
Solos e avaliação da aptidão agrícola das terras do município de Inhangapi, Estado do Pará. [PDF]
, 2001 bitstream/item/63718/1/Oriental-Doc125.PDFAnexo 2 mapas: Mapa de aptidão agrícola das terras do Município de Inhangapi - Pará; Mapa de solos do Município de Inhangapi ...
CARVALHO, E. J. M. +7 more
core