Results 101 to 110 of about 930 (262)

Solid particles focusing, orienting, and de‐focusing in planar Poiseuille flow

open access: yesAIChE Journal, EarlyView.
Abstract Three‐dimensional, time‐dependent lattice‐Boltzmann simulations of neutrally buoyant particles in planar Poiseuille flow have been performed. The particles are spherical or cylindrical (the latter with a length over diameter ratios in the range 1/3 to 2) and have volume fraction ranging from virtually zero (one particle) to 0.15. The channel's
J. J. Derksen
wiley   +1 more source

Backbone Steric Constraints Underlie High Passive Membrane Permeability of N‐Alkyl Peptides

open access: yesAngewandte Chemie, EarlyView.
Beyond amide hydrogen removal, steric constraints encoded in N/Cα‐dually substituted backbones are uncovered as a key determinant of passive membrane permeability in N‐alkyl peptides. These constraints restrict conformational freedom and sterically limit backbone hydration during membrane permeation.
Ayumi Inayoshi   +8 more
wiley   +2 more sources

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

open access: yesAdvanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang   +9 more
wiley   +1 more source

Machine Learning‐Assisted Second‐Order Perturbation Theory for Chemical Potential Correction Toward Hubbard U Determination

open access: yesAdvanced Intelligent Discovery, EarlyView.
In this work, the Doubao large language model (LLM) is involved in the formula derivation processes for Hubbard U determination regarding the second‐order perturbations of the chemical potential. The core ML tool is optimized for physical domain knowledge, which is not limited to parameter prediction but rather serves as an interactive physical theory ...
Mingzi Sun   +8 more
wiley   +1 more source

In Situ Contact Angle Measurement for Autonomous Spin Coating in Self‐Driving Labs

open access: yesAdvanced Intelligent Discovery, EarlyView.
A vision‐based add‐on transforms commercial spin coaters into autonomous modules of Self‐Driving Labs. Combining a width‐scaled U‐Net with classical geometric analysis, the system simultaneously measures contact angles and estimates substrate pose using a single camera.
Sven Fischer, Micha Hiegle, Holger Röhm
wiley   +1 more source

One‐Shot Multimaterial 3D Printing of a Flexible Spine for a Robotic Fish Prototype

open access: yesAdvanced Intelligent Systems, EarlyView.
A one‐shot multimaterial 3D printing approach enables a monolithic soft robotic fish integrating a compliant spine and rigid vertebrae. Electromagnetic linear actuators drive tendon‐based transmission, producing controlled tail oscillations. Finite element modeling and experiments show strong agreement, while optimized material selection improves ...
Marco Colletta   +3 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

Multi‐Responsive Bowl‐Shaped Janus Nanomotors Based on Polyitaconic acid/Polypyrrole on the Surface of Iron Oxide Nanoparticles with Chemical, Electrical, and Magnetic Field Actuation for Targeted Drug Delivery Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bowl‐shaped Janus nanomotors with platinum, iron oxide, and polypyrrole integrate catalytic, magnetic, and electric propulsion for targeted drug delivery. They demonstrate controlled, directional motion under varying pH and hydrogen peroxide conditions, with optimal performance in neutral media.
Kimia Tavakoli Dehaghi   +3 more
wiley   +1 more source

Growth dynamics, skeletochronology, and histovariability of the theropod dinosaur Berthasaura leopoldinae

open access: yesThe Anatomical Record, EarlyView.
Osteohistological sampling on different bones of theropod dinosaur documents discrepant age record, growth, and metabolism. This could result unprecise paleobiological inferences if samplings are based on single bones. However, multi‐bone sampling can attenuate these discrepancies, helping to infer growth dynamics and physiology of these extinct ...
Geovane Alves de Souza   +3 more
wiley   +1 more source

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